Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 4/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.40 |
| ▸ | STAT3 | P40763 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10472998 | 0.86 | ADRB2 (0.57) | POLBADRB2ALDH1A1CHRM2CHRM1 | |
| SCHEMBL4564641 | 0.86 | ADRB2 (0.57) | POLBADRB2ALDH1A1CHRM2CHRM1 | |
| SCHEMBL7575069 | 0.86 | ADRB2 (0.61) | POLBADRB2ALDH1A1CHRM2CHRM1 | |
| SCHEMBL3123309 | 0.85 | ADRB2 (0.54) | POLBADRB2ALDH1A1LMNAMAPT | |
| SCHEMBL4476600 | 0.84 | ADRB2 (0.55) | POLBADRB2ALDH1A1LMNACHRM2 | |
| SCHEMBL3134363 | 0.83 | POLB (0.49) | POLBADRB2ALDH1A1LMNAMAPT | |
| SCHEMBL5704396 | 0.82 | ADRB2 (0.64) | POLBADRB2ALDH1A1CHRM2CHRM1 | |
| SCHEMBL9688340 | 0.82 | ADRB2 (0.45) | POLBADRB2ALDH1A1LMNAMAPT | |
| SCHEMBL10473197 | 0.82 | POLB (0.71) | POLBADRB2ALDH1A1LMNAMAPT | |
| SCHEMBL8435344 | 0.81 | ADRB2 (0.60) | POLBADRB2ALDH1A1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868021-B2 | Antimicrobial quinolones, their compositions and uses | WARNER CHILCOTT COMPANY, LLC (US) | 2011-01-11 | — | — | US | disclosed |
| US-7868021-B2 | Antimicrobial quinolones, their compositions and uses | WARNER CHILCOTT COMPANY, LLC (US) | 2011-01-11 | — | — | US | disclosed |
| US-7868021-B2 | Antimicrobial quinolones, their compositions and uses | WARNER CHILCOTT COMPANY, LLC (US) | 2011-01-11 | — | — | US | disclosed |
| US-20090111851-A1 | Antimicrobial Quinolones, Their Compositions and Uses | WARNER CHILCOTT COMPANY, LLC | 2009-04-30 | — | — | US | disclosed |
| US-20090111851-A1 | Antimicrobial Quinolones, Their Compositions and Uses | WARNER CHILCOTT COMPANY, LLC | 2009-04-30 | — | — | US | disclosed |
| US-20090111851-A1 | Antimicrobial Quinolones, Their Compositions and Uses | WARNER CHILCOTT COMPANY, LLC | 2009-04-30 | — | — | US | disclosed |
| US-7019143-B2 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-28 | — | — | US | disclosed |
| CN-1671690-A | Antimicrobial azabicyclic derivatives, compositions and uses thereof | PROCTER & GAMBLE (US) | 2005-09-21 | — | — | CN | disclosed |
| US-6900224-B2 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-31 | — | — | US | disclosed |
| EP-1532137-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-25 | — | — | EP | disclosed |
| US-20050101589-A1 | Antimicrobial quinolones, their compositions and uses | WARNER CHILCOTT COMPANY, LLC | 2005-05-12 | — | — | US | disclosed |
| US-6849740-B2 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE COMPANY (US) | 2005-02-01 | — | — | US | disclosed |
| US-20040038975-A1 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE COMPANY | 2004-02-26 | — | — | US | disclosed |
| WO-2004014893-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |
| US-20030207862-A1 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE COMPANY | 2003-11-06 | — | — | US | disclosed |
| US-20020173501-A1 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE COMPANY | 2002-11-21 | — | — | US | disclosed |
| US-6387928-B1 | BACTERICIDES; SIDE EFFECT REDUCTION | THE PROCTER & GAMBLE CO. | 2002-05-14 | — | — | US | disclosed |
| US-20020049192-A1 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE COMPANY | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049192-A1 | Antimicrobial quinolones, their compositions and uses | QARS1, TOP1, TOP2A | POLB 230/4885ADRB2 3151/4885ALDH1A1 3377/4885 |
| US-20090111851-A1 | Antimicrobial Quinolones, Their Compositions and Uses | QARS1, NQO2, TOP2A | POLB 246/4885ADRB2 3005/4885ALDH1A1 3978/4885 |
| US-20040038975-A1 | Antimicrobial quinolones, their compositions and uses | QARS1, NQO2, Q6ZSR9 | POLB 210/4885ADRB2 2970/4885ALDH1A1 2739/4885 |
| US-20020173501-A1 | Antimicrobial quinolones, their compositions and uses | QARS1, TOP1, TOP2A | POLB 230/4885ADRB2 3151/4885ALDH1A1 3377/4885 |
| US-20030207862-A1 | Antimicrobial quinolones, their compositions and uses | QARS1, TOP1, TOP2A | POLB 230/4885ADRB2 3151/4885ALDH1A1 3377/4885 |
| US-20050101589-A1 | Antimicrobial quinolones, their compositions and uses | QARS1, NQO2, TOP2A | POLB 246/4885ADRB2 3005/4885ALDH1A1 3978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.