SCHEMBL10038545

SCHEMBL10038545

c1ccc(-c2ccccc2-c2ccc3oc4c(-n5c6ccc(-c7ccc8oc9c(-n%10c%11ccc(-c%12ccccc%12-c%12ccccn%12)cc%11c%11ncccc%11%10)cccc9c8c7)cc6c6ncccc65)cccc4c3c2)nc1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 1/20 0.34
ALOX5 P09917 1/20 0.33
PRKDC P78527 2/20 0.33
AHR P35869 1/20 0.31
PIK3R2 O00459 1/20 0.31
JAK2 O60674 1/20 0.30
JAK1 P23458 1/20 0.30
TYK2 P29597 1/20 0.30
JAK3 P52333 1/20 0.30
NPY5R Q15761 1/20 0.30
BRD4 O60885 1/20 0.30
GRM5 P41594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1610450 0.95 GRM5 (0.33) MAPK14ALOX5PRKDCPIK3R2GRM5
SCHEMBL17035676 0.95 MAPK14 (0.33) MAPK14ALOX5PRKDCPIK3R2BRD4
SCHEMBL5028299 0.94 MAPK14 (0.32) MAPK14ALOX5PRKDCPIK3R2GRM5
SCHEMBL16919802 0.94 MAPK14 (0.32) MAPK14ALOX5PRKDCPIK3R2NPY5R
SCHEMBL12925710 0.91 GRM5 (0.34) MAPK14PRKDCGRM5
SCHEMBL5028237 0.89 ALOX5 (0.32) MAPK14ALOX5PRKDCPIK3R2
SCHEMBL12925729 0.88 ALOX5 (0.31) MAPK14ALOX5PRKDCNPY5R
SCHEMBL12925664 0.87 GRM5 (0.31) GRM5
SCHEMBL5028305 0.87 GRM5 (0.31) GRM5
SCHEMBL12925570 0.86 MAPK14 (0.34) MAPK14ALOX5PRKDCJAK2JAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2930762-B1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, AND DISPLAY DEVICE KONICA MINOLTA INC (JP) 2020-09-16 EP disclosed
US-10468610-B2 Isomer-mixture metal complex composition, organic electroluminescent element, illuminator, and display device Konica Minolta, Inc. (JP) 2019-11-05 US disclosed
US-10347850-B2 Organic electroluminescent element, lighting device and display device Konica Minolta, Inc. (JP) 2019-07-09 US disclosed
US-10177322-B2 Iridium complex, method for producing iridium complex, organic electroluminescent element, display device, and lighting device Konica Minolta, Inc. (JP) 2019-01-08 US disclosed
US-9960356-B2 Organic electroluminescence device, lighting equipment and display device Konica Minolta, Inc. (JP) 2018-05-01 US disclosed
US-9960356-B2 Organic electroluminescence device, lighting equipment and display device Konica Minolta, Inc. (JP) 2018-05-01 US disclosed
US-9944629-B2 Material for organic electroluminescent element, organic electroluminescent element, illumination device, and display device Konica Minolta, Inc. (JP) 2018-04-17 US disclosed
US-9944629-B2 Material for organic electroluminescent element, organic electroluminescent element, illumination device, and display device Konica Minolta, Inc. (JP) 2018-04-17 US disclosed
US-20170309839-A1 IRIDIUM COMPLEX, METHOD FOR PRODUCING IRIDIUM COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE KONICA MINOLTA INC (JP) 2017-10-26 US disclosed
US-20170309839-A1 IRIDIUM COMPLEX, METHOD FOR PRODUCING IRIDIUM COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE KONICA MINOLTA INC (JP) 2017-10-26 US disclosed
US-20150179958-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-06-25 US disclosed
US-20150179958-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-06-25 US disclosed
EP-2884552-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-06-17 EP disclosed
US-9040975-B2 Organic electroluminescence element, illumination device, and display device Konica Minolta, Inc. (JP) 2015-05-26 US disclosed
US-9040975-B2 Organic electroluminescence element, illumination device, and display device Konica Minolta, Inc. (JP) 2015-05-26 US disclosed
US-20130099216-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-04-25 US disclosed
US-20130099216-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-04-25 US disclosed
EP-2584019-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE Konica Minolta Holdings, Inc. (JP) 2013-04-24 EP disclosed
US-20120018714-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY APPARATUS, AND LIGHTING APPARATUS KONICA MINOLTA HOLDINGS, INC. (JP) 2012-01-26 US disclosed
US-20120018714-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY APPARATUS, AND LIGHTING APPARATUS KONICA MINOLTA HOLDINGS, INC. (JP) 2012-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10468610-B2 Isomer-mixture metal complex composition, organic electroluminescent element, illuminator, and display device EMC2, ELP1, EMC1 MAPK14 2582/4885ALOX5 975/4885PRKDC 4191/4885
US-10177322-B2 Iridium complex, method for producing iridium complex, organic electroluminescent element, display device, and lighting device EED, SNW1, AP2M1 MAPK14 4606/4885ALOX5 1708/4885PRKDC 2772/4885
US-20170309839-A1 IRIDIUM COMPLEX, METHOD FOR PRODUCING IRIDIUM COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE EED, SNW1, AP2M1 MAPK14 4606/4885ALOX5 1708/4885PRKDC 2772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.