Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | IGF1R | P08069 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | IDH2 | P48735 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10038823 | 0.81 | AR (0.48) | BACE1ALDH1A1MAPTIGF1RGAA | |
| SCHEMBL3300391 | 0.80 | BACE1 (0.66) | BACE1ALDH1A1MAPTIGF1RGAA | |
| SCHEMBL19209593 | 0.77 | GAA (0.52) | ALDH1A1MAPTIGF1RGAARAB9A | |
| SCHEMBL10038805 | 0.72 | ALDH1A1 (0.57) | BACE1ALDH1A1MAPTGAARAB9A | |
| SCHEMBL10038578 | 0.72 | ALDH1A1 (0.49) | BACE1ALDH1A1MAPTGAARAB9A | |
| SCHEMBL27943848 | 0.72 | ALDH1A1 (0.49) | BACE1ALDH1A1MAPTGAARAB9A | |
| SCHEMBL29210710 | 0.70 | ALDH1A1 (0.44) | CDK2ALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL4558336 | 0.70 | PDK2 (0.51) | ALDH1A1MAPTGAAKMT2AKDM4E | |
| SCHEMBL10038579 | 0.69 | MAPT (0.43) | BACE1ALDH1A1MAPTGAARAB9A | |
| SCHEMBL11891520 | 0.69 | BACE1 (0.51) | CDK2BACE1ALDH1A1MAPTIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106206-B2 | Solid luminescent quinoline compounds | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20110263861-A1 | QUINOLINE COMPOUND | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263861-A1 | QUINOLINE COMPOUND | GTF3C3, GTF3C2, GTF3C1 | CDK2 130/4885BACE1 4769/4885ALDH1A1 2963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.