Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | IDH2 | P48735 | 1/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | ACP1 | P24666 | 2/20 | 0.46 |
| ▸ | IGF1R | P08069 | 4/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.45 |
| ▸ | C1R | P00736 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAK | O14976 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | MARK3 | P27448 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29200458 | 0.80 | GAK (0.64) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL10038804 | 0.77 | CDK2 (0.45) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL16404469 | 0.77 | ABCG2 (0.76) | ALDH1A1KDM4EMEN1KMT2AABCG2 | |
| SCHEMBL3826784 | 0.73 | NT5E (0.54) | KDM4EIGF1RC1RPRKD3MAP4K4 | |
| SCHEMBL19209591 | 0.73 | CTSD (0.41) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL3453097 | 0.73 | C1R (0.71) | MAPTALDH1A1KDM4EC1RNPSR1 | |
| SCHEMBL3850835 | 0.72 | BACE1 (0.45) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL11133397 | 0.72 | KDM4E (0.49) | GAAKDM4EMEN1KMT2AC1R | |
| SCHEMBL3828474 | 0.72 | BACE1 (0.45) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL11829749 | 0.72 | KDM4E (0.41) | ALDH1A1KDM4EKMT2AC1RPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136642-A1 | ANTIBIOTIC COMPOSITIONS | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017136642-A1 | ANTIBIOTIC COMPOSITIONS | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2017-08-10 | — | — | WO | disclosed |