Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 2/20 | 0.53 |
| ▸ | FLT3 | P36888 | 2/20 | 0.52 |
| ▸ | PDE2A | O00408 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5827084 | 0.88 | PDE2A (0.58) | PDE2ALMNAGAA | |
| SCHEMBL2703655 | 0.88 | PDE2A (0.58) | PDE2ALMNAGAA | |
| SCHEMBL19709261 | 0.88 | PDE2A (0.58) | PDE2ALMNAGAA | |
| SCHEMBL10039780 | 0.88 | PDE2A (0.55) | PDE2ALMNAGAA | |
| SCHEMBL10039781 | 0.84 | PDE2A (0.49) | PDE2ALMNAGAAMEN1KMT2A | |
| SCHEMBL17149666 | 0.82 | PYGL (0.60) | PYGLFLT3LMNAGAAMEN1 | |
| SCHEMBL17149882 | 0.82 | PYGL (0.60) | PYGLFLT3LMNAGAAMEN1 | |
| SCHEMBL17149890 | 0.82 | PYGL (0.60) | PYGLFLT3LMNAGAAMEN1 | |
| SCHEMBL17149653 | 0.81 | PYGL (0.53) | PYGLFLT3LMNAMEN1KMT2A | |
| SCHEMBL9956140 | 0.80 | KDM4E (0.59) | PYGLFLT3LMNAGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012084971-A1 | INDOLE DERIVATIVES AS AGENTS AGAINST GRAM-NEGATIVE AND GRAM-POSITIVE BACTERIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-06-28 | — | — | WO | disclosed |