Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19709261 | 0.89 | PDE2A (0.58) | PDE2ALMNAGAA | |
| SCHEMBL2703655 | 0.89 | PDE2A (0.58) | PDE2ALMNAGAA | |
| SCHEMBL5827084 | 0.89 | PDE2A (0.58) | PDE2ALMNAGAA | |
| SCHEMBL10039649 | 0.88 | PYGL (0.53) | PDE2ALMNAGAA | |
| SCHEMBL10039781 | 0.85 | PDE2A (0.49) | PDE2ALMNAGAA | |
| SCHEMBL17149620 | 0.82 | TP53 (0.64) | TP53POLBPDGFRBPDGFRAPIN1 | |
| SCHEMBL26098783 | 0.81 | PDE2A (0.57) | PDE2ALMNAGAA | |
| SCHEMBL9956140 | 0.81 | KDM4E (0.59) | PDGFRBPDGFRALMNAGAA | |
| SCHEMBL10039604 | 0.79 | MEN1 (0.56) | PDE2APDGFRBPDGFRALMNAGAA | |
| SCHEMBL14845690 | 0.79 | PIN1 (0.62) | TP53POLBPDGFRBPDGFRAPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012084971-A1 | INDOLE DERIVATIVES AS AGENTS AGAINST GRAM-NEGATIVE AND GRAM-POSITIVE BACTERIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-06-28 | — | — | WO | disclosed |