Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 7/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1881392 | 0.94 | CYP2C19 (0.59) | CYP2C19CYP2D6CYP2C9CYP1A2TSHR | |
| SCHEMBL663757 | 0.94 | CYP2C19 (0.59) | CYP2C19CYP2D6CYP2C9CYP1A2TSHR | |
| SCHEMBL663756 | 0.94 | CYP2C19 (0.59) | CYP2C19CYP2D6CYP2C9CYP1A2TSHR | |
| SCHEMBL5673666 | 0.94 | CYP2C19 (0.59) | CYP2C19CYP2D6CYP2C9CYP1A2TSHR | |
| SCHEMBL8783194 | 0.92 | CYP2C19 (0.58) | CYP2C19CYP2D6CYP2C9CYP1A2TSHR | |
| SCHEMBL30874729 | 0.92 | CYP2C19 (0.58) | CYP2C19CYP2D6CYP2C9CYP1A2TSHR | |
| SCHEMBL30505546 | 0.89 | CYP2C19 (0.54) | CYP2C19CYP2D6CYP2C9CYP1A2TSHR | |
| SCHEMBL17295969 | 0.85 | CYP2C19 (0.53) | CYP2C19CYP2D6CYP2C9CYP1A2TSHR | |
| SCHEMBL24425958 | 0.84 | CYP2D6 (0.77) | CYP2C19CYP2D6CYP2C9CYP1A2TSHR | |
| SCHEMBL20979191 | 0.84 | CYP2D6 (0.77) | CYP2C19CYP2D6CYP2C9CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889873-B2 | Process for the preparation of enantiomerically enriched proton pump inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2014-11-18 | — | — | US | disclosed |
| US-20120046319-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED PROTON PUMP INHIBITORS | LEK PHARMACEUTICALS D.D. (SI) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046319-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED PROTON PUMP INHIBITORS | PPOX, HPD, HRH2 | CYP2C19 10/4885CYP2D6 14/4885CYP2C9 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.