Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 4/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4943737 | 0.86 | CA1 (0.37) | ALDH1A1TDP1FOLH1MEN1LMNA | |
| SCHEMBL7947604 | 0.82 | ALDH1A1 (0.34) | ALDH1A1TDP1FOLH1MEN1LMNA | |
| SCHEMBL1121772 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRKMT2ANFKB1 | |
| SCHEMBL2304432 | 0.80 | KDM4C (0.39) | ALDH1A1TDP1MEN1LMNAHPGD | |
| SCHEMBL7570633 | 0.78 | KDM4C (0.41) | ALDH1A1TDP1FDPS | |
| SCHEMBL7950976 | 0.78 | KDM4C (0.41) | ALDH1A1TDP1FDPS | |
| SCHEMBL2302042 | 0.78 | KDM4C (0.41) | ALDH1A1TDP1FDPS | |
| SCHEMBL7947910 | 0.78 | KDM4C (0.41) | ALDH1A1TDP1FDPS | |
| SCHEMBL11516995 | 0.77 | CA1 (0.44) | ALDH1A1TDP1FOLH1MEN1LMNA | |
| SCHEMBL1576890 | 0.74 | TDP1 (0.41) | ALDH1A1TDP1TSHRKMT2ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178798-A1 | SUBSTITUTED CYCLOPENTANES HAVING PROSTAGLANDIN ACTIVITY | ALLERGAN, INC. (US) | 2012-07-12 | — | — | US | disclosed |
| US-8158676-B2 | Substituted cyclopentanes having prostaglandin activity | ALLERGAN, INC. (US) | 2012-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178798-A1 | SUBSTITUTED CYCLOPENTANES HAVING PROSTAGLANDIN ACTIVITY | PTGIS, PTGES, PTGS1 | ALDH1A1 626/4885TDP1 2874/4885FOLH1 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.