SCHEMBL10040366

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10040386	0.88	ALDH1A1 (0.42)	ALDH1A1PGRGAAPTGS1MAPK1
	SCHEMBL32667385	0.88	ALDH1A1 (0.42)	ALDH1A1PGRGAAPTGS1MAPK1
	SCHEMBL27965594	0.86	CYP3A4 (0.50)	MTNR1AMTNR1BMCL1TRPV1ALDH1A1
	SCHEMBL10040389	0.86	MCL1 (0.47)	MTNR1AMTNR1BMCL1TRPV1ALDH1A1
	SCHEMBL13588208	0.85	CYP2A6 (0.46)	MCL1ALDH1A1PGRGAAPTGS1
	SCHEMBL12458542	0.85	ELANE (0.48)	MTNR1AMTNR1BALDH1A1PGRGAA
	SCHEMBL11963913	0.82	PLA2G2D (0.46)	ALDH1A1PGRGAAPTGS1MAPK1
	SCHEMBL67480	0.82	ALDH1A1 (0.60)	ALDH1A1PGRGAAPTGS1MAPK1
	SCHEMBL29373404	0.82	ALDH1A1 (0.60)	ALDH1A1PGRGAAPTGS1MAPK1
	SCHEMBL7134423	0.81	ELANE (0.46)	ALDH1A1PGRGAAPTGS1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.