Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12918623 | 0.91 | HTT (0.59) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL2741100 | 0.91 | HTT (0.59) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL11411338 | 0.87 | HTT (0.54) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL3285794 | 0.87 | HTT (0.54) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL29306192 | 0.86 | HTT (0.50) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL24605352 | 0.84 | KMT2A (0.68) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL27947111 | 0.84 | KMT2A (0.68) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL2741099 | 0.84 | KMT2A (0.68) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL13135270 | 0.84 | KMT2A (0.68) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL12370833 | 0.84 | KMT2A (0.68) | KMT2AHTTSMN1; SMN2TDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820932-B2 | Polymerisable liquid crystal material and polymerised liquid crystal film | MERCK PATENT GMBH (DE) | 2023-11-21 | — | — | US | disclosed |
| US-11795399-B2 | UV curable adhesion promoters based on functionalised polyvinyl alcohols | MERCK PATENT GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| US-20230265344-A1 | POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM | MERCK PATENT GMBH (DE) | 2023-08-24 | — | — | US | disclosed |
| US-11718790-B2 | Method for the preparation of a liquid crystal polymer film | MERCK PATENT GMBH (DE) | 2023-08-08 | — | — | US | disclosed |
| US-11697769-B2 | Polymerizable liquid crystal material and polymerized liquid crystal film | MERCK PATENT GMBH (DE) | 2023-07-11 | — | — | US | disclosed |
| US-20180195004-A1 | POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM | MERCK PATENT GMBH (DE) | 2018-07-12 | — | — | US | disclosed |
| US-20180148648-A1 | REACTIVE MESOGENS | MERCK PATENT GMBH (DE) | 2018-05-31 | — | — | US | disclosed |
| US-20180016499-A1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2018-01-18 | — | — | US | disclosed |
| US-20170357131-A1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2017-12-14 | — | — | US | disclosed |
| US-20170351130-A1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2017-12-07 | — | — | US | disclosed |
| US-7887717-B2 | Liquid-crystalline medium and liquid-crystal display having high twist | MERCK PATENT GESELLSCHAFT MIT BESCHRANKER HAFTUNG (DE) | 2011-02-15 | — | — | US | disclosed |
| US-20100301271-A1 | FLUORENE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-12-02 | — | — | US | disclosed |
| US-7807068-B2 | reacting 4-halo-2,6-difluorophenol with protecting group, dehalogenating to form protected phenol ether group, reacting with boronic acid/ester, coupling in presence of catalyst, deblocking, etherifying, esterifying; for optical, electro-optical and electronic use, liquid-crystal media and displays | MERCK PATENT GESELLSCHAFT (DE) | 2010-10-05 | — | — | US | disclosed |
| US-20100222534-A1 | Mesogenic Dimers | MERCK PATENT GESELLSCHAFT (DE) | 2010-09-02 | — | — | US | disclosed |
| US-20100208191-A1 | CHIRAL REACTIVE MESOGEN MIXTURE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-08-19 | — | — | US | disclosed |
| US-20100201920-A1 | Calamitic Mesogenic Compounds | MERCK PATENT GESELLSCHAFT (DE) | 2010-08-12 | — | — | US | disclosed |
| US-20100110362-A1 | Birefringent Polymer Film with Negative Optical Dispersion | PARRI OWAIN LLYR | 2010-05-06 | — | — | US | disclosed |
| US-20100072422-A1 | Birefringent Layer with Negative Optical Dispersion | MERCK PATENT GMBH (DE) | 2010-03-25 | — | — | US | disclosed |
| US-20090225270-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY HAVING HIGH TWIST | MERCK PATENT GESELLSCHAFT (DE) | 2009-09-10 | — | — | US | disclosed |
| US-20090141215-A1 | POLYMERIZABLE COMPOUNDS | MERCK PATENT GESELLSCHAFT (DE) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180148648-A1 | REACTIVE MESOGENS | MAFG, LSG1, MAS1 | KMT2A 2688/4885HTT 130/4885SMN1; SMN2 3604/4885 |
| US-20100301271-A1 | FLUORENE DERIVATIVES | FLNA, FLNB, AFF2 | KMT2A 3321/4885HTT 1100/4885SMN1; SMN2 3692/4885 |
| US-20100222534-A1 | Mesogenic Dimers | PML, MLEC, MTX2 | KMT2A 3628/4885HTT 340/4885SMN1; SMN2 3910/4885 |
| US-20100110362-A1 | Birefringent Polymer Film with Negative Optical Dispersion | PUF60, LCP1, MAP1LC3C | KMT2A 3041/4885HTT 1276/4885SMN1; SMN2 3983/4885 |
| US-20100201920-A1 | Calamitic Mesogenic Compounds | CALD1, CALR, CALU | KMT2A 4263/4885HTT 1411/4885SMN1; SMN2 3080/4885 |
| US-20090141215-A1 | POLYMERIZABLE COMPOUNDS | VCL, LCP1, LPXN | KMT2A 3414/4885HTT 1026/4885SMN1; SMN2 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.