Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 4/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354932 | 0.89 | CCR3 (0.59) | SPRCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL23365125 | 0.85 | SPR (0.49) | SPRCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL23365142 | 0.82 | CCR3 (0.57) | SPRCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL2544691 | 0.81 | KDM4E (0.47) | SPR | |
| SCHEMBL4959434 | 0.81 | ALDH1A1 (0.59) | SPRCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL6114819 | 0.81 | HTR1A (0.49) | SPRCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL23122394 | 0.81 | SPR (0.44) | SPRCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL1008518 | 0.79 | GRIN2D (0.59) | FAAHMEN1KMT2A | |
| SCHEMBL5369713 | 0.79 | HTT (0.54) | FAAHMEN1KMT2A | |
| SCHEMBL19873074 | 0.79 | MEN1 (0.61) | SPRCYP2C9CYP2C19HTR2BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271619-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009126535-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-10-15 | — | — | WO | disclosed |