SCHEMBL15100480

SCHEMBL15100480

CC/N=c1/ccc2c(-c3ccccc3C(=O)OC)c3ccc(N(CC)CC)cc3oc-2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCB1 P08183 1/20 0.53
▸ ATM Q13315 3/20 0.51
▸ USP2 O75604 2/20 0.51
▸ CFTR P13569 1/20 0.51
▸ PAX8 Q06710 1/20 0.51
▸ GOPC Q9HD26 1/20 0.51
▸ TGM2 P21980 1/20 0.41
▸ MEN1 O00255 3/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ POLB P06746 2/20 0.41
▸ PPARG P37231 1/20 0.41
▸ BLM P54132 1/20 0.41
▸ RXFP1 Q9HBX9 1/20 0.41
▸ NCOR2 Q9Y618 1/20 0.41
▸ FPR2 P25090 4/20 0.40
▸ ALDH1A1 P00352 3/20 0.37
▸ MAPT P10636 2/20 0.37
▸ CDC25A P30304 1/20 0.37
▸ CDC25C P30307 1/20 0.37
▸ NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22851948 0.92 MAOB (0.45) ABCB1ATMUSP2CFTRPAX8
SCHEMBL14192857 0.92 ABCB1 (0.54) ABCB1ATMUSP2CFTRPAX8
SCHEMBL17517217 0.90 TGM2 (0.42) ABCB1ATMUSP2CFTRPAX8
SCHEMBL15100483 0.90 TGM2 (0.42) ABCB1ATMUSP2CFTRPAX8
SCHEMBL18084345 0.89 FPR2 (0.43) ABCB1ATMUSP2CFTRPAX8
SCHEMBL12103999 0.89 MEN1 (0.43) ABCB1ATMUSP2CFTRPAX8
Hydrochloric Acid SCHEMBL11336327 0.89 TGM2 (0.42) ABCB1ATMUSP2CFTRPAX8
SCHEMBL2732905 0.89 ABCB1 (0.43) ABCB1ATMUSP2CFTRPAX8
SCHEMBL18637298 0.87 ABCB1 (0.56) ABCB1ATMUSP2CFTRPAX8
SCHEMBL15483871 0.87 ABCB1 (0.56) ABCB1ATMUSP2CFTRPAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9499665-B2 Block copolymers for stable micelles INTEZYNE TECHNOLOGIES, INC. (US) 2016-11-22 — — US disclosed
US-20160264732-A1 BLOCK COPOLYMERS FOR STABLE MICELLES INTEZYNE TECHNOLOGIES, INC. 2016-09-15 — — US disclosed
US-20150368401-A1 BLOCK COPOLYMERS FOR STABLE MICELLES INTEZYNE TECHNOLOGIES, INC. 2015-12-24 — — US disclosed
US-20130178600-A1 POLY(ETHYLENE GLYCOL) DERIVATIVES FOR CLICK CHEMISTRY INTEZYNE TECHNOLOGIES, INC. (US) 2013-07-11 — — US disclosed
US-20110091534-A1 COMPOSITIONS COMPRISING POLYMERIC MICELLES FOR DRUG DELIVERY INTEZYNE TECHNOLOGIES, INC. (US) 2011-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110091534-A1 COMPOSITIONS COMPRISING POLYMERIC MICELLES FOR DRUG DELIVERY ABCB4, ABCB11, CLTB ABCB1 6/4885ATM 2631/4885USP2 1273/4885
US-20160264732-A1 BLOCK COPOLYMERS FOR STABLE MICELLES ABCB4, CLTB, EPHA2 ABCB1 6/4885ATM 1706/4885USP2 735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback