Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ESRRB | O95718 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10041191 | 0.80 | NPC1 (0.50) | NPC1RAB9ATDP1MEN1KMT2A | |
| SCHEMBL15490892 | 0.70 | CTNNB1 (0.48) | NPC1RAB9APKMTDP1TSHR | |
| SCHEMBL4568716 | 0.68 | ALDH1A1 (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL6619829 | 0.65 | CA2 (0.36) | NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6503964 | 0.65 | TSHR (0.50) | NPC1RAB9ATDP1TSHRMEN1 | |
| SCHEMBL6503966 | 0.65 | TSHR (0.50) | NPC1RAB9ATDP1TSHRMEN1 | |
| SCHEMBL6131977 | 0.65 | CTNNB1 (0.54) | NPC1RAB9APKMTSHRCTNNB1 | |
| SCHEMBL19500875 | 0.64 | CA12 (0.47) | NPC1RAB9ATDP1TSHRMEN1 | |
| SCHEMBL13556809 | 0.63 | NOX1 (0.33) | ESRRBNPC1RAB9ATDP1MEN1 | |
| SCHEMBL6801600 | 0.61 | PTPN1 (0.53) | PTPN1RAB9ATDP1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120161089-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120161089-A1 | CHROMENE COMPOUND | CYP8B1, HSD3B2, CYP17A1 | PTPN1 3608/4885ESRRB 20/4885NPC1 1074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.