SCHEMBL6619829

SCHEMBL6619829

COC1Oc2ccccc2O1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.36
CA4 P22748 2/20 0.33
LTA4H P09960 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
PARP1 P09874 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
ITGB2 P05107 1/20 0.32
ICAM1 P05362 1/20 0.32
ITGAL P20701 1/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
MAOB P27338 1/20 0.32
NR3C1 P04150 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10054032 0.75 USP2 (0.37) CA2CA12CA9ALDH1A1MAOB
SCHEMBL3626503 0.74 CA2 (0.36) CA2ABCG2ITGB2ICAM1ITGAL
SCHEMBL11549002 0.73 CA2 (0.37) CA2NPC1L3MBTL1ALDH1A1
SCHEMBL21624268 0.73 LMNA (0.35) CA2LTA4HALDH1A1MAPTMAOB
SCHEMBL7709636 0.71 PTPN1 (0.33)
SCHEMBL7709944 0.71 CYP3A4 (0.33) ALDH1A1
SCHEMBL11034100 0.70 POLB (0.46) CA2NPC1RAB9AL3MBTL1ALDH1A1
SCHEMBL7988202 0.69 ALDH1A1 (0.46) RAB9AALDH1A1
SCHEMBL312107 0.69 ABCG2 (0.36) CA2ABCG2ITGB2ICAM1ITGAL
SCHEMBL353825 0.69 PARP1 (0.40) CA2PARP1ABCG2ITGB2ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630504-B2 Phenethylamine derivatives, compositions, and methods of use CYBIN IRL LIMITED (IE) 2026-05-19 US disclosed
US-12535735-B2 Modified thioxanthone photoinitiators LINTFIELD LIMITED (GB) 2026-01-27 US disclosed
US-12398152-B2 Thioxanthone derivatives, composition comprising the same and pattern forming method comprising said composition LINTFIELD LIMITED (GB) 2025-08-26 US disclosed
US-20250145566-A1 PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE CYBIN IRL LIMITED (IE) 2025-05-08 US disclosed
US-20240317704-A1 PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE CYBIN IRL LIMITED (IE) 2024-09-26 US disclosed
US-20230322742-A1 ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES AGILENT TECHNOLOGIES, INC. 2023-10-12 US disclosed
US-20230322742-A1 ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES AGILENT TECHNOLOGIES, INC. 2023-10-12 US disclosed
US-20230082557-A1 Modified Thioxanthone Photoinitiators LINTFIELD LIMITED (GB) 2023-03-16 US disclosed
US-11548876-B2 Orthoester compositions for affinity purification of oligonucleotides AGILENT TECHNOLOGIES, INC. (US) 2023-01-10 US disclosed
EP-4090656-A1 MODIFIED THIOXANTHONE PHOTOINITIATORS Lintfield Limited (GB) 2022-11-23 EP disclosed
US-20210277017-A1 Thioxanthone Derivatives, Composition Comprising the Same and Pattern Forming Method Comprising Said Composition LINTFIELD LIMITED (GB) 2021-09-09 US disclosed
WO-2021144582-A1 MODIFIED THIOXANTHONE PHOTOINITIATORS LINTFIELD LIMITED (GB) 2021-07-22 WO disclosed
EP-3824349-A1 THIOXANTHONE DERIVATIVES, COMPOSITION COMPRISING THE SAME AND PATTERN FORMING METHOD COMPRISING SAID COMPOSITION Lintfield Limited (GB) 2021-05-26 EP disclosed
US-20200190129-A1 ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES AGILENT TECHNOLOGIES, INC. 2020-06-18 US disclosed
US-20200181124-A1 ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES AGILENT TECHNOLOGIES, INC. 2020-06-11 US disclosed
WO-2020016389-A1 THIOXANTHONE DERIVATIVES, COMPOSITION COMPRISING THE SAME AND PATTERN FORMING METHOD COMPRISING SAID COMPOSITION LINTFIELD LIMITED (GB) 2020-01-23 WO disclosed
US-20120161089-A1 CHROMENE COMPOUND TOKUYAMA CORPORATION (JP) 2012-06-28 US disclosed
US-20120161089-A1 CHROMENE COMPOUND TOKUYAMA CORPORATION (JP) 2012-06-28 US disclosed
EP-1463726-A2 AROMATIC THIOETHER LIVER X-RECEPTOR MODULATORS Pharmacia Corporation (US) 2004-10-06 EP disclosed
WO-2003059874-A2 AROMATIC THIOETHER LIVER X-RECEPTOR MODULATORS PHARMACIA CORPORATION (US) 2003-07-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240317704-A1 PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE HTR2C, HTR2A, PNMT CA2 4694/4885CA4 4775/4885LTA4H 960/4885
US-20200190129-A1 ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES RNGTT, OSBPL8, DCLRE1B CA2 4500/4885CA4 3077/4885LTA4H 3843/4885
US-20230082557-A1 Modified Thioxanthone Photoinitiators TPMT, PPOX, TST CA2 2021/4885CA4 884/4885LTA4H 23/4885
US-12630504-B2 Phenethylamine derivatives, compositions, and methods of use HTR2C, HTR1A, HTR2A CA2 3591/4885CA4 4656/4885LTA4H 2119/4885
US-12398152-B2 Thioxanthone derivatives, composition comprising the same and pattern forming method comprising said composition TPMT, TST, PPOX CA2 3199/4885CA4 998/4885LTA4H 23/4885
US-20200181124-A1 ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES RNGTT, OSBPL8, DCLRE1B CA2 4500/4885CA4 3077/4885LTA4H 3843/4885
US-12535735-B2 Modified thioxanthone photoinitiators FTO, UGT1A6, TPMT CA2 2247/4885CA4 1090/4885LTA4H 341/4885
US-11548876-B2 Orthoester compositions for affinity purification of oligonucleotides RNGTT, OSBPL8, DCLRE1B CA2 4500/4885CA4 3077/4885LTA4H 3843/4885
US-20230322742-A1 ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES RNGTT, OSBPL8, DCLRE1B CA2 4500/4885CA4 3077/4885LTA4H 3843/4885
US-20120161089-A1 CHROMENE COMPOUND CYP8B1, HSD3B2, CYP17A1 CA2 2725/4885CA4 3696/4885LTA4H 4307/4885
US-20250145566-A1 PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE PNMT, HTR7, HTR2C CA2 4775/4885CA4 4705/4885LTA4H 779/4885
US-20210277017-A1 Thioxanthone Derivatives, Composition Comprising the Same and Pattern Forming Method Comprising Said Composition TPMT, TST, PPOX CA2 3199/4885CA4 998/4885LTA4H 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.