Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | VDR | P11473 | 5/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10041384 | 1.00 | CYP19A1 (0.36) | CYP19A1VDRCDC25ACDC25B | |
| SCHEMBL10041383 | 1.00 | CYP19A1 (0.36) | CYP19A1VDRCDC25ACDC25B | |
| SCHEMBL10041391 | 0.88 | VDR (0.41) | CYP19A1VDRCDC25ACDC25B | |
| SCHEMBL10041392 | 0.88 | VDR (0.41) | CYP19A1VDRCDC25ACDC25B | |
| SCHEMBL10041389 | 0.88 | VDR (0.41) | CYP19A1VDRCDC25ACDC25B | |
| SCHEMBL10041390 | 0.88 | VDR (0.41) | CYP19A1VDRCDC25ACDC25B | |
| SCHEMBL10070741 | 0.86 | VDR (0.35) | CYP19A1VDRCDC25ACDC25B | |
| SCHEMBL10070738 | 0.86 | VDR (0.35) | CYP19A1VDRCDC25ACDC25B | |
| SCHEMBL10070742 | 0.86 | VDR (0.35) | CYP19A1VDRCDC25ACDC25B | |
| SCHEMBL10070737 | 0.86 | VDR (0.35) | CYP19A1VDRCDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664206-B2 | Diastereomers of 2-methylene-19-nor-22-methyl-1α,25-dihydroxyvitamin D3 | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-03-04 | — | — | US | disclosed |
| US-20120165300-A1 | DIASTEREOMERS OF 2-METHYLENE-19-NOR-22-METHYL-1ALPHA,25-DIHYDROXYVITAMIN D3 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165300-A1 | DIASTEREOMERS OF 2-METHYLENE-19-NOR-22-METHYL-1ALPHA,25-DIHYDROXYVITAMIN D3 | CYP24A1, CYP2R1, CYP27B1 | CYP19A1 40/4885VDR 4/4885CDC25A 1007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.