Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22728675 | 0.83 | RIPK1 (0.45) | RIPK1LMNAADORA3ALDH1A1RAB9A | |
| SCHEMBL8392778 | 0.81 | SMN1; SMN2 (0.43) | RIPK1LMNAADORA3ALDH1A1RAB9A | |
| SCHEMBL17870940 | 0.74 | RIPK1 (0.53) | RIPK1LMNAADORA3ALDH1A1RAB9A | |
| SCHEMBL17870941 | 0.74 | RIPK1 (0.53) | RIPK1LMNAADORA3ALDH1A1RAB9A | |
| SCHEMBL30054156 | 0.74 | RIPK1 (0.53) | RIPK1LMNAADORA3ALDH1A1RAB9A | |
| SCHEMBL22700996 | 0.73 | CHRM2 (0.39) | RIPK1LMNACHRM2CHRM3ALDH1A1 | |
| SCHEMBL22700950 | 0.73 | CHRM2 (0.41) | RIPK1CHRM2CHRM3ALDH1A1RAB9A | |
| SCHEMBL25017953 | 0.71 | CHRM2 (0.57) | RIPK1LMNAADORA3CHRM2CHRM3 | |
| SCHEMBL15197712 | 0.71 | SMN1; SMN2 (0.55) | LMNAADORA3ALDH1A1KMT2AATM | |
| SCHEMBL12333636 | 0.70 | GLS (0.46) | LMNAADORA3RAB9ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012057709-A1 | NOVEL PHASE TRANSFER CATALYSTS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2012-05-03 | — | — | WO | disclosed |