Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | NR1I2 | O75469 | 1/20 | 1.00 |
| ▸ | CYP2B6 | P20813 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Artemisin SCHEMBL13976003 | 1.00 | PTGES2 (1.00) | PTGES2ALDH1A1LMNAHTTCYP1A2 | |
| Artemisin SCHEMBL2604464 | 1.00 | PTGES2 (1.00) | PTGES2ALDH1A1LMNAHTTCYP1A2 | |
| Artemisin SCHEMBL12741200 | 1.00 | PTGES2 (1.00) | PTGES2ALDH1A1LMNAHTTCYP1A2 | |
| Artemisin SCHEMBL13219259 | 1.00 | PTGES2 (1.00) | PTGES2ALDH1A1LMNAHTTCYP1A2 | |
| Artemisin SCHEMBL23843508 | 1.00 | PTGES2 (1.00) | PTGES2ALDH1A1LMNAHTTCYP1A2 | |
| Artemisin SCHEMBL23974927 | 1.00 | PTGES2 (1.00) | PTGES2ALDH1A1LMNAHTTCYP1A2 | |
| Artemisin SCHEMBL14013802 | 1.00 | PTGES2 (1.00) | PTGES2ALDH1A1LMNAHTTCYP1A2 | |
| Artemisin SCHEMBL60303 | 1.00 | PTGES2 (1.00) | PTGES2ALDH1A1LMNAHTTCYP1A2 | |
| Artemisin SCHEMBL10331315 | 1.00 | PTGES2 (1.00) | PTGES2ALDH1A1LMNAHTTCYP1A2 | |
| Artemisin SCHEMBL14616147 | 1.00 | PTGES2 (1.00) | PTGES2ALDH1A1LMNAHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241023-A1 | STABILIZATION OF 1,2,4-TRIOXANE COMPOUNDS BY CHLOROGENIC ACIDS | Artemiflow GmbH (DE) | 2023-08-03 | — | — | US | disclosed |
| US-20230241023-A1 | STABILIZATION OF 1,2,4-TRIOXANE COMPOUNDS BY CHLOROGENIC ACIDS | Artemiflow GmbH (DE) | 2023-08-03 | — | — | US | disclosed |
| US-20230149346-A1 | 1,2,4-TRIOXANE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME FOR USE IN THE PREVENTION AND TREATMENT OF CANCER | Artemiflow GmbH (DE) | 2023-05-18 | — | — | US | disclosed |
| US-8207402-B2 | Nucleotide sequences encoding enzymes in biosynthesis of dihydroartemisinic acid | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2012-06-26 | — | — | US | disclosed |
| US-20110162097-A1 | NUCLEOTIDE SEQUENCE ENCODING AN ALCOHOL DEHYDROGENASE FROM ARTEMISIA ANNUA AND USES THEREOF | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2011-06-30 | — | — | US | disclosed |
| US-20100299778-A1 | NUCLEOTIDE SEQUENCE ENCODING ARTEMISINIC ALDEHYDE DOUBLE BOND REDUCTASE, ARTEMISINIC ALDEHYDE DOUBLE BOND REDUCTASE AND USES THEREOF | NATIONAL RESEARCH COUNCIL OF CANADA | 2010-11-25 | — | — | US | disclosed |
| US-20090265804-A1 | NUCLEOTIDE SEQUENCES ENCODING ENZYMES IN BIOSYNTHESIS OF DIHYDROARTEMISINIC ACID | NATIONAL RESEARCH COUNCIL OF CANADA | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230149346-A1 | 1,2,4-TRIOXANE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME FOR USE IN THE PREVENTION AND TREATMENT OF CANCER | PRDX4, CA4, TOP1 | PTGES2 585/4885ALDH1A1 1120/4885LMNA 3555/4885 |
| US-20230241023-A1 | STABILIZATION OF 1,2,4-TRIOXANE COMPOUNDS BY CHLOROGENIC ACIDS | GCK, PCK1, CA4 | PTGES2 2481/4885ALDH1A1 1165/4885LMNA 3863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.