Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21084438 | 0.61 | ESR1 (0.35) | SMN1; SMN2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL12993299 | 0.61 | MAOA (0.34) | — | |
| SCHEMBL8130364 | 0.61 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL11881427 | 0.59 | SMN1; SMN2 (0.88) | SMN1; SMN2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL19396241 | 0.59 | SMN1; SMN2 (0.88) | SMN1; SMN2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL11892894 | 0.59 | SMN1; SMN2 (0.80) | SMN1; SMN2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL13437909 | 0.59 | SMN1; SMN2 (0.80) | SMN1; SMN2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL10891508 | 0.59 | VHL (0.58) | SMN1; SMN2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL11166223 | 0.58 | ALDH1A1 (0.41) | SMN1; SMN2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL17985411 | 0.58 | TRPA1 (0.41) | SMN1; SMN2NPC1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11911261-B2 | Vision correction with laser refractive index changes | UNIVERSITY OF ROCHESTER (US) | 2024-02-27 | — | — | US | disclosed |
| US-11911261-B2 | Vision correction with laser refractive index changes | UNIVERSITY OF ROCHESTER (US) | 2024-02-27 | — | — | US | disclosed |
| US-11833081-B2 | Vision correction with laser refractive index changes | UNIVERSITY OF ROCHESTER (US) | 2023-12-05 | — | — | US | disclosed |
| US-11833081-B2 | Vision correction with laser refractive index changes | UNIVERSITY OF ROCHESTER (US) | 2023-12-05 | — | — | US | disclosed |
| US-20230157812-A1 | VISION CORRECTION WITH LASER REFRACTIVE INDEX CHANGES | UNIV ROCHESTER (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230157812-A1 | VISION CORRECTION WITH LASER REFRACTIVE INDEX CHANGES | UNIV ROCHESTER (US) | 2023-05-25 | — | — | US | disclosed |
| US-11369515-B2 | Vision correction with laser refractive index changes | UNIVERSITY OF ROCHESTER (US) | 2022-06-28 | — | — | US | disclosed |
| US-20210196520-A1 | Vision Correction With Laser Refractive Index Changes | Clerio Vision, Inc. | 2021-07-01 | — | — | US | disclosed |
| US-20210177578-A1 | VISION CORRECTION WITH LASER REFRACTIVE INDEX CHANGES | UNIV ROCHESTER (US) | 2021-06-17 | — | — | US | disclosed |
| US-20210177576-A1 | VISION CORRECTION WITH LASER REFRACTIVE INDEX CHANGES | UNIV ROCHESTER (US) | 2021-06-17 | — | — | US | disclosed |
| US-8901190-B2 | Optical hydrogel material with photosensitizer and method for modifying the refractive index | UNIVERSITY OF ROCHESTER (US) | 2014-12-02 | — | — | US | disclosed |
| US-20130268072-A1 | Optical Hydrogel Material with Photosensitizer and Method for Modifying the Refractive Index | UNIVERSITY OF ROCHESTER | 2013-10-10 | — | — | US | disclosed |
| US-20130268072-A1 | Optical Hydrogel Material with Photosensitizer and Method for Modifying the Refractive Index | UNIVERSITY OF ROCHESTER | 2013-10-10 | — | — | US | disclosed |
| US-20120310340-A1 | Method for Modifying the Refractive Index of an Optical Material and Resulting Optical Vision Component | BAUSCH HEALTH MAGYARORSZAG KFT (A/K/A BAUSCH HEALTH HUNGARY LLC) (HU) | 2012-12-06 | — | — | US | disclosed |
| US-20120310340-A1 | Method for Modifying the Refractive Index of an Optical Material and Resulting Optical Vision Component | BAUSCH HEALTH MAGYARORSZAG KFT (A/K/A BAUSCH HEALTH HUNGARY LLC) (HU) | 2012-12-06 | — | — | US | disclosed |
| WO-2012166696-A1 | METHOD FOR MODIFYING THE REFRACTIVE INDEX OF AN OPTICAL MATERIAL AND RESULTING OPTICAL VISION COMPONENT | BAUSCH & LOMB INCORPORATED (US) | 2012-12-06 | — | — | WO | disclosed |
| EP-2326285-B1 | INTRAOCULAR LENS WITH PHOTOSENSITIZER AND METHOD FOR MODIFYING THE REFRACTIVE INDEX OF THE LENS | BAUSCH & LOMB (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2009143054-A2 | INTRAOCULAR LENS WITH PHOTOSENSITIZER AND METHOD FOR MODIFYING THE REFRACTIVE INDEX OF THE LENS | BAUSCH & LOMB INCORPORATED (US) | 2009-11-26 | — | — | WO | disclosed |
| US-20090287306-A1 | Optical hydrogel material with photosensitizer and method for modifying the refractive index | MEDICIS PHARMACEUTICAL CORPORATION | 2009-11-19 | — | — | US | disclosed |
| US-20090287306-A1 | Optical hydrogel material with photosensitizer and method for modifying the refractive index | MEDICIS PHARMACEUTICAL CORPORATION | 2009-11-19 | — | — | US | disclosed |