Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101634 | 0.94 | POLB (0.46) | HPGDNPC1RAB9ASMN1; SMN2LTB4R | |
| SCHEMBL100322 | 0.86 | HPGD (0.44) | HPGDNPC1RAB9ASMN1; SMN2LTB4R | |
| SCHEMBL15824060 | 0.85 | ALDH1A1 (0.42) | HPGDNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL99878 | 0.85 | KDM4E (0.43) | HPGDNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL99091 | 0.85 | RAB9A (0.51) | HPGDNPC1RAB9ASMN1; SMN2LTB4R | |
| SCHEMBL99385 | 0.84 | LTB4R (0.61) | HPGDNPC1RAB9ASMN1; SMN2LTB4R | |
| SCHEMBL661329 | 0.84 | CHRM3 (0.51) | HPGD | |
| SCHEMBL100933 | 0.83 | POLB (0.46) | HPGDNPC1RAB9ASMN1; SMN2LTB4R | |
| SCHEMBL99701 | 0.82 | AKR1C3 (0.53) | HPGDNPC1RAB9ASMN1; SMN2HCAR2 | |
| SCHEMBL15823257 | 0.82 | POLB (0.45) | HPGDNPC1RAB9ASMN1; SMN2LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | claimed |