Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998183 | 0.85 | PTPN1 (0.49) | PTPN1 | |
| SCHEMBL13998196 | 0.72 | PTPN1 (0.53) | PTPN1 | |
| Shanzhiside SCHEMBL306203 | 0.72 | MAPT (0.58) | PTPN1 | |
| SCHEMBL14010919 | 0.66 | PTPN1 (0.46) | PTPN1 | |
| SCHEMBL13998040 | 0.62 | PTPN1 (0.40) | PTPN1 | |
| SCHEMBL24894750 | 0.58 | CHRM5 (0.32) | — | |
| SCHEMBL2410832 | 0.57 | GABRR1 (0.34) | — | |
| SCHEMBL10042265 | 0.57 | PTPN1 (0.51) | PTPN1 | |
| SCHEMBL13998193 | 0.57 | TLR4 (0.72) | — | |
| SCHEMBL636663 | 0.56 | FFAR3 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093288-B2 | Genipin derivatives and uses thereof | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2012-01-10 | — | — | US | disclosed |
| US-20100168160-A1 | Genipin Derivatives and Uses Thereof | BETH ISRAEL DEACONESS MEDICAL CENTER , INC. AND TRUSTEES OF BOSTON UNIVERSITY (US) | 2010-07-01 | — | — | US | disclosed |
| US-7649014-B2 | Genipin derivatives and uses thereof | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-20080009450-A9 | Genipin derivatives and uses thereof | ZHANG CHEN-YU | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009450-A9 | Genipin derivatives and uses thereof | GPR119, PCK2, UCK2 | PTPN1 1677/4885 |
| US-20100168160-A1 | Genipin Derivatives and Uses Thereof | GPR119, PCK2, UCK2 | PTPN1 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.