Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ATP4A | P20648 | 1/20 | 0.30 |
| ▸ | ATP4B | P51164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177014 | 0.84 | ESR1 (0.35) | PRSS1PRSS2PRSS3GRIN1GRIN2B | |
| SCHEMBL12655080 | 0.75 | OPRM1 (0.31) | GRIN2B | |
| SCHEMBL23568075 | 0.67 | PRSS1 (0.49) | DHODHPRSS1PRSS2PRSS3KMO | |
| SCHEMBL23750310 | 0.66 | KMO (0.49) | DHODHPRSS1PRSS2PRSS3KMO | |
| SCHEMBL14471650 | 0.65 | KMO (0.54) | DHODHPRSS1PRSS2PRSS3KMO | |
| SCHEMBL12435375 | 0.64 | ESR1 (0.34) | PRSS1PRSS2PRSS3 | |
| SCHEMBL13799193 | 0.63 | AKT1 (0.35) | PRSS1PRSS2PRSS3 | |
| SCHEMBL12070646 | 0.62 | KMO (0.57) | DHODHKMOMKNK1MKNK2EGFR | |
| SCHEMBL18015562 | 0.62 | PRSS1 (0.73) | DHODHPRSS1PRSS2PRSS3KMO | |
| SCHEMBL21845658 | 0.62 | PRSS1 (0.50) | DHODHPRSS1PRSS2PRSS3KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087007-A1 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2012-06-28 | — | — | WO | disclosed |