Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | RARB | P10826 | 6/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18903880 | 0.95 | HSD11B1 (0.51) | HSD11B1RARBAKR1C2AKR1C1BCHE | |
| SCHEMBL10042892 | 0.95 | HSD11B1 (0.57) | HSD11B1RARBALDH1A1MEN1RARA | |
| SCHEMBL13474962 | 0.93 | RARB (0.54) | HSD11B1RARBBCHEALDH1A1MEN1 | |
| SCHEMBL12533891 | 0.93 | RARB (0.54) | HSD11B1RARBBCHEALDH1A1MEN1 | |
| SCHEMBL289833 | 0.93 | RARB (0.54) | HSD11B1RARBBCHEALDH1A1MEN1 | |
| SCHEMBL12386345 | 0.93 | HSD11B1 (0.58) | HSD11B1RARBALDH1A1MEN1RARA | |
| SCHEMBL10042894 | 0.93 | HSD11B1 (0.58) | HSD11B1RARBALDH1A1MEN1RARA | |
| SCHEMBL38667 | 0.93 | RARB (0.54) | HSD11B1RARBBCHEALDH1A1MEN1 | |
| SCHEMBL309398 | 0.93 | RARB (0.54) | HSD11B1RARBBCHEALDH1A1MEN1 | |
| SCHEMBL11887113 | 0.93 | HSD11B1 (0.58) | HSD11B1RARBALDH1A1MEN1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120037889-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE AND ILLUMINATION DEVICE | KONICA MINOLTA HOLDINGS, INC. (JP) | 2012-02-16 | — | — | US | disclosed |