Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 8/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 8/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25967589 | 1.00 | PLA2G2A (0.43) | PLA2G2APLA2G10PLA2G1BPLA2G5TLR2 | |
| SCHEMBL25967477 | 0.93 | PLA2G2A (0.43) | PLA2G2APLA2G10PLA2G1BPLA2G5TLR2 | |
| SCHEMBL30866265 | 0.86 | TLR2 (0.41) | PLA2G2APLA2G10PLA2G1BPLA2G5TLR2 | |
| SCHEMBL10604671 | 0.86 | PLA2G10 (0.47) | PLA2G2APLA2G10PLA2G1BPLA2G5TLR2 | |
| SCHEMBL10605748 | 0.86 | PLA2G10 (0.47) | PLA2G2APLA2G10PLA2G1BPLA2G5TLR2 | |
| SCHEMBL18641859 | 0.86 | PLA2G10 (0.47) | PLA2G2APLA2G10PLA2G1BPLA2G5TLR2 | |
| SCHEMBL10604578 | 0.86 | PLA2G10 (0.47) | PLA2G2APLA2G10PLA2G1BPLA2G5TLR2 | |
| SCHEMBL24304580 | 0.85 | PLA2G2A (0.47) | PLA2G2APLA2G10PLA2G1BPLA2G5TLR2 | |
| SCHEMBL24304605 | 0.85 | PLA2G2A (0.45) | PLA2G2APLA2G10PLA2G1BPLA2G5TLR2 | |
| SCHEMBL24304365 | 0.83 | PLA2G2A (0.37) | PLA2G2APLA2G10PLA2G1BPLA2G5TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334235-B2 | Plasmalogen compounds, pharmaceutical compositions containing the same and methods for treating diseases of the aging | PHENOMENOME DISCOVERIES INC. (CA) | 2016-05-10 | — | — | US | disclosed |
| US-20130116312-A2 | PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING | PHENOMENOME DISCOVERIES INC. (CA) | 2013-05-09 | — | — | US | disclosed |
| US-20120035250-A1 | PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING | PHENOMENOME DISCOVERIES INC. (CA) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035250-A1 | PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING | PHOSPHO1, SGMS2, MBOAT1 | PLA2G2A 25/4885PLA2G10 12/4885PLA2G1B 106/4885 |
| US-20130116312-A2 | PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING | PHOSPHO1, SGMS2, MBOAT1 | PLA2G2A 25/4885PLA2G10 12/4885PLA2G1B 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.