SCHEMBL25967477

SCHEMBL25967477

CCCCCCCCCCCCCCCCCCOC[C@H](CO[Si](C)(C)C(C)(C)C)OCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 10/20 0.43
PLA2G10 O15496 4/20 0.43
PLA2G1B P04054 3/20 0.42
PLA2G5 P39877 3/20 0.42
TLR2 O60603 8/20 0.41
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25967589 0.93 PLA2G2A (0.43) PLA2G2APLA2G10PLA2G1BPLA2G5TLR2
SCHEMBL10043029 0.93 PLA2G2A (0.43) PLA2G2APLA2G10PLA2G1BPLA2G5TLR2
SCHEMBL24304694 0.87 PLA2G2A (0.44) PLA2G2APLA2G10PLA2G1BPLA2G5TLR2
SCHEMBL25971807 0.86 TLR2 (0.44) PLA2G2APLA2G10PLA2G1BPLA2G5TLR2
SCHEMBL24304580 0.84 PLA2G2A (0.47) PLA2G2APLA2G10PLA2G1BPLA2G5TLR2
SCHEMBL25971831 0.84 TLR2 (0.46) PLA2G2APLA2G10PLA2G1BPLA2G5TLR2
SCHEMBL24304595 0.82 PLA2G2A (0.37) PLA2G2APLA2G10PLA2G1BPLA2G5
SCHEMBL24304365 0.82 PLA2G2A (0.37) PLA2G2APLA2G10PLA2G1BPLA2G5TLR2
SCHEMBL24304381 0.80 TLR2 (0.48) PLA2G2APLA2G10PLA2G1BPLA2G5TLR2
SCHEMBL29413318 0.80 PLA2G2A (0.36) PLA2G2APLA2G10PLA2G1BPLA2G5TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473314-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2025-11-18 US disclosed
EP-4537828-A2 PHOSPHOLIPID COMPOUNDS AND USES THEREOF Gilead Sciences, Inc. (US) 2025-04-16 EP disclosed
EP-4200301-B1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES INC (US) 2025-02-26 EP disclosed
US-12030904-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-07-09 US disclosed
US-12030904-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-07-09 US disclosed
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2024-01-25 US disclosed
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2024-01-25 US disclosed
US-11773122-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES. INC. (US) 2023-10-03 US disclosed
US-11773122-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES. INC. (US) 2023-10-03 US disclosed
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2023-08-10 US disclosed
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2023-08-10 US disclosed
EP-4200301-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2023-06-28 EP disclosed
US-20220081455-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2022-03-17 US disclosed
WO-2022046631-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2022-03-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030904-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 PLA2G2A 29/4885PLA2G10 31/4885PLA2G1B 22/4885
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 PLA2G2A 29/4885PLA2G10 31/4885PLA2G1B 22/4885
US-20220081455-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 PLA2G2A 29/4885PLA2G10 31/4885PLA2G1B 22/4885
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 PLA2G2A 29/4885PLA2G10 31/4885PLA2G1B 22/4885
US-11773122-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 PLA2G2A 29/4885PLA2G10 31/4885PLA2G1B 22/4885
US-12473314-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 PLA2G2A 29/4885PLA2G10 31/4885PLA2G1B 22/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.