SCHEMBL10044363

SCHEMBL10044363

COCCCSCC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GMNN O75496 1/20 0.55
▸ TP53 P04637 1/20 0.55
▸ POLB P06746 1/20 0.55
▸ MAPT P10636 1/20 0.55
▸ THRB P10828 1/20 0.55
▸ CYP2C9 P11712 1/20 0.55
▸ BLM P54132 1/20 0.55
▸ HSD17B10 Q99714 1/20 0.55
▸ ALDH1A1 P00352 1/20 0.48
▸ CYP2D6 P10635 2/20 0.46
▸ HIF1A Q16665 1/20 0.46
▸ MVD P53602 1/20 0.46
▸ TSHR P16473 2/20 0.39
▸ BHMT Q93088 1/20 0.37
▸ CES2 O00748 1/20 0.36
▸ PLA2G4B P0C869 1/20 0.36
▸ RECQL P46063 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ CES1 P23141 1/20 0.34
▸ MMP12 P39900 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5639474 0.86 — —
SCHEMBL9640732 0.79 MVD (0.47) GMNNTP53POLBMAPTTHRB
SCHEMBL8941669 0.79 GMNN (0.52) GMNNTP53POLBMAPTTHRB
SCHEMBL8666564 0.78 HSD17B10 (0.73) GMNNTP53POLBMAPTTHRB
SCHEMBL15282760 0.78 HSD17B10 (0.65) GMNNTP53POLBMAPTTHRB
SCHEMBL10044364 0.78 ALDH1A1 (0.42) GMNNTP53POLBMAPTTHRB
SCHEMBL14845357 0.78 ALDH1A1 (0.35) GMNNTP53POLBMAPTTHRB
SCHEMBL6231607 0.76 HSD17B10 (0.77) GMNNTP53POLBMAPTTHRB
SCHEMBL22922013 0.76 HSD17B10 (0.70) GMNNTP53POLBMAPTTHRB
Hydrochloric Acid SCHEMBL11144143 0.76 HSD17B10 (0.70) GMNNTP53POLBMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9005985-B2 Optical reporter compositions APDN (B.V.I.) INC. (US) 2015-04-14 — — US disclosed
US-20130149706-A1 OPTICAL REPORTER COMPOSITIONS APDN (B.V.I.) Inc., dba Applied DNA Sciences, Inc. (US) 2013-06-13 — — US disclosed
US-8426216-B2 Methods for authenticating articles with optical reporters APDN (B.V.I.), Inc. (US) 2013-04-23 — — US disclosed
US-8420400-B2 System and method for authenticating tablets APDN (B.V.I.), Inc. (US) 2013-04-16 — — US disclosed
US-8415165-B2 System and method for authenticating sports identification goods APDN (B.V.I.), Inc. (US) 2013-04-09 — — US disclosed
US-8415164-B2 System and method for secure document printing and detection APDN (B.V.I.) INC. (US) 2013-04-09 — — US disclosed
US-20120252025-A1 METHODS FOR COVALENT LINKING OF OPTICAL REPORTERS APDN, Inc. 2012-10-04 — — US disclosed
US-20120184613-A1 SULFUR-CONTAINING COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-19 — — US disclosed
US-8124333-B2 Methods for covalent linking of optical reporters APDN, Inc. (VG) 2012-02-28 — — US disclosed
US-20090075261-A1 SYSTEM AND METHOD FOR AUTHENTICATING TABLETS APDN (B.V.I.) INC. (VG) 2009-03-19 — — US disclosed
US-20090042191-A1 SYSTEM AND METHOD FOR SECURE DOCUMENT PRINTING AND DETECTION APDN (B.V.I.) INC. 2009-02-12 — — US disclosed
US-20090042191-A1 SYSTEM AND METHOD FOR SECURE DOCUMENT PRINTING AND DETECTION APDN (B.V.I.) INC. 2009-02-12 — — US disclosed
US-20080312427-A1 METHODS FOR COVALENT LINKING OF OPTICAL REPORTERS APDN (B.V.I.) INC. 2008-12-18 — — US disclosed
US-20080299559-A1 METHODS FOR AUTHENTICATING ARTICLES WITH OPTICAL REPORTERS APDN (B.V.I.) INC. 2008-12-04 — — US disclosed
US-20080293052-A1 SYSTEM AND METHOD FOR AUTHENTICATING SPORTS IDENTIFICATION GOODS APDN (B.V.I.) INC. 2008-11-27 — — US disclosed
US-20080293052-A1 SYSTEM AND METHOD FOR AUTHENTICATING SPORTS IDENTIFICATION GOODS APDN (B.V.I.) INC. 2008-11-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120184613-A1 SULFUR-CONTAINING COMPOUND AND USE THEREOF C5, C1S, CYC1 GMNN 1848/4885TP53 4181/4885POLB 4367/4885
US-20080312427-A1 METHODS FOR COVALENT LINKING OF OPTICAL REPORTERS PCNA, POLL, LIG3 GMNN 171/4885TP53 1328/4885POLB 15/4885
US-20120252025-A1 METHODS FOR COVALENT LINKING OF OPTICAL REPORTERS PCNA, POLL, LIG3 GMNN 171/4885TP53 1328/4885POLB 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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