⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640732 | 0.87 | MVD (0.47) | — | |
| SCHEMBL10044363 | 0.86 | GMNN (0.55) | — | |
| SCHEMBL2474100 | 0.81 | — | — | |
| SCHEMBL17418515 | 0.79 | LMNA (0.64) | — | |
| Hydrochloric Acid SCHEMBL9696329 | 0.79 | MVD (0.35) | — | |
| SCHEMBL5638161 | 0.79 | TSHR (0.40) | — | |
| SCHEMBL8048722 | 0.77 | MAPT (0.50) | — | |
| SCHEMBL1313188 | 0.76 | CYP2D6 (0.73) | — | |
| SCHEMBL10317271 | 0.76 | MVD (0.44) | — | |
| SCHEMBL8727713 | 0.76 | CYP2D6 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120184613-A1 | SULFUR-CONTAINING COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-19 | — | — | US | disclosed |
| WO-2011044505-A2 | ENZYME INHIBITING COMPOUNDS AND METHODS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-04-14 | — | — | WO | disclosed |
| US-20090042191-A1 | SYSTEM AND METHOD FOR SECURE DOCUMENT PRINTING AND DETECTION | APDN (B.V.I.) INC. | 2009-02-12 | — | — | US | disclosed |
| US-20090042191-A1 | SYSTEM AND METHOD FOR SECURE DOCUMENT PRINTING AND DETECTION | APDN (B.V.I.) INC. | 2009-02-12 | — | — | US | disclosed |
| US-7229987-B2 | Multicyclic compounds for use as melanin concentrating hormone antagonists in the treatment of obesity and diabetes | ELI LILLY AND COMPANY (US) | 2007-06-12 | — | — | US | disclosed |
| US-7229987-B2 | Multicyclic compounds for use as melanin concentrating hormone antagonists in the treatment of obesity and diabetes | ELI LILLY AND COMPANY (US) | 2007-06-12 | — | — | US | disclosed |
| US-7229987-B2 | Multicyclic compounds for use as melanin concentrating hormone antagonists in the treatment of obesity and diabetes | ELI LILLY AND COMPANY (US) | 2007-06-12 | — | — | US | disclosed |
| US-20050272718-A1 | Multicyclic compounds for use as melanin concentrating hormone antagonists in the treatment of obesity and diabetes | AMMENN ET AL, JOCHEN | 2005-12-08 | — | — | US | disclosed |
| EP-1505968-A1 | MULTICYCLIC COMPOUNDS FOR USE AS MELANIN CONCENTRATING HORMONE ANTAGONISTS IN THE TREATMENT OF OBESITY AND DIABETES | ELI LILLY AND COMPANY (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097047-A1 | MULTICYCLIC COMPOUNDS FOR USE AS MELANIN CONCENTRATING HORMONE ANTAGONISTS IN THE TREATMENT OF OBESITY AND DIABETES | ELI LILLY AND COMPANY (US) | 2003-11-27 | — | — | WO | disclosed |
| EP-0131374-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PENEM DERIVATIVES | PFIZER INC. (US) | 1988-11-23 | — | — | EP | disclosed |
| US-4725678-A | ANTIBIOTICS | PFIZER INC. (US) | 1988-02-16 | — | — | US | disclosed |
| US-4595539-A | Containing acid or ester groups and sulfur | PFIZER INC. (US) | 1986-06-17 | — | — | US | disclosed |
| EP-0131374-A1 | Process and intermediates for the preparation of penem derivatives | PFIZER INC. (US) | 1985-01-16 | — | — | EP | disclosed |
| EP-0128725-A1 | Preparation of penem derivatives | PFIZER INC. (US) | 1984-12-19 | — | — | EP | disclosed |
| US-4279806-A | Antimony mercaptides as processing stabilizers for vinyl halide resins | ASSOCIATED LEAD INC. (US) | 1981-07-21 | — | — | US | disclosed |