Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MVD | P53602 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | BHMT | Q93088 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5639474 | 0.87 | — | — | |
| SCHEMBL2474164 | 0.84 | CA2 (0.35) | MVDHSD17B10MAPT | |
| SCHEMBL9640708 | 0.82 | KDM1A (0.35) | MVDHSD17B10POLBALDH1A1TSHR | |
| SCHEMBL28617242 | 0.82 | HSD17B10 (0.54) | MVDBLMHSD17B10MAPTALDH1A1 | |
| SCHEMBL14175659 | 0.82 | HSD17B10 (0.54) | MVDBLMHSD17B10MAPTALDH1A1 | |
| SCHEMBL9640252 | 0.82 | KDM1A (0.35) | MVDHSD17B10POLBALDH1A1TSHR | |
| SCHEMBL8727713 | 0.82 | CYP2D6 (0.44) | MVDBLMHSD17B10GMNNTP53 | |
| SCHEMBL8048722 | 0.79 | MAPT (0.50) | MVDBLMHSD17B10GMNNTP53 | |
| SCHEMBL5994074 | 0.79 | CYP2D6 (0.46) | MVDBLMHSD17B10GMNNTP53 | |
| SCHEMBL10044363 | 0.79 | GMNN (0.55) | MVDBLMHSD17B10GMNNTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9095625-B2 | Graft-copolymer stabilized metal nanoparticles | UNIVERSITY OF MASSACHUSETTS (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140065425-A1 | GRAFT-COPOLYMER STABILIZED METAL NANOPARTICLES | UNIVERSITY OF MASSACHUSETTS (US) | 2014-03-06 | — | — | US | disclosed |
| EP-0287042-B1 | 2-SULPHINYL-ACETYL-1,3-THIAZOLIDINES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-09-16 | — | — | EP | disclosed |
| EP-0287042-A1 | 2-Sulphinyl-acetyl-1,3-thiazolidines, their preparation and pharmaceutical compositions | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1988-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140065425-A1 | GRAFT-COPOLYMER STABILIZED METAL NANOPARTICLES | LNPEP, GMNN, PARN | MVD 280/4885BLM 4235/4885HSD17B10 4756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.