Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 18/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.80 |
| ▸ | GLA | P06280 | 3/20 | 0.80 |
| ▸ | RECQL | P46063 | 2/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.79 |
| ▸ | RAB9A | P51151 | 2/20 | 0.79 |
| ▸ | BLM | P54132 | 2/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.74 |
| ▸ | ACHE | P22303 | 1/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.74 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29994151 | 1.00 | TOP1 (1.00) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL27827045 | 1.00 | TOP1 (1.00) | TOP1ALDH1A1GLARECQLTDP1 | |
| Hydrochloric Acid SCHEMBL28012447 | 0.98 | TOP1 (0.97) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL17897650 | 0.92 | TOP1 (0.85) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL25932513 | 0.92 | TOP1 (0.85) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL10636628 | 0.91 | TOP1 (0.84) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL1006662 | 0.90 | TOP1 (1.00) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL27561956 | 0.90 | TOP1 (1.00) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL27367949 | 0.89 | TOP1 (0.81) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL23270615 | 0.89 | TOP1 (1.00) | TOP1ALDH1A1GLARECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026086871-A1 | ANTI-AGEING COMPOUNDS, USES THEREFOR, METHOD FOR IDENTIFYING, AND COMPOSITIONS CONTAINING | Centre for Translational Stem Cell Biology Limited (CN) | 2026-04-30 | — | — | WO | claimed |
| CN-117343944-A | Gene, protein, recombinant vector and method for catalyzing synthesis of 9-methoxy camptothecine | 上海师范大学 | 2024-01-05 | — | — | CN | claimed |
| CN-113880872-A | Preparation of camptothecin boric acid compound and application of camptothecin boric acid compound in anti-tumor aspect | 兰州大学 | 2022-01-04 | — | — | CN | claimed |
| CN-113880855-A | Preparation of 9-fluoro camptothecin derivative and application of 9-fluoro camptothecin derivative in anti-tumor aspect | 兰州大学 | 2022-01-04 | — | — | CN | claimed |
| CN-104619322-B | Anticancer pharmaceutical composition and its production and use | 张苑金 | 2016-10-19 | — | — | CN | claimed |
| CN-104619322-A | ANTICANCER PHARMACEUTICAL COMPOSITION, PREPARATION METHOD FOR SAME, AND USE THEREOF | ZHANG YUANJIN | 2015-05-13 | — | — | CN | claimed |
| CN-102895229-A | Medical application of camptothecin and its derivative in resisting Alzheimer disease | UNIV CHINA PHARMA | 2013-01-30 | — | — | CN | claimed |
| US-7994186-B2 | Pharmaceutical compositions containing camptothecins | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2011-08-09 | — | — | US | claimed |
| CN-102080112-A | Method for synthesizing 9-methoxy camptothecin by artificially inducing icacinaceae endophyte | YUANJIN ZHANG | 2011-06-01 | — | — | CN | claimed |
| CN-102051393-A | Method for extracting camptothecin and 9-methoxyl camptothecin from root-bark of pittosporumlike nothapodytes | ENSHI JINHUA BIO ENGINEERING CO LTD | 2011-05-11 | — | — | CN | claimed |
| US-6534080-B2 | Injecting into a patientaqueous suspension of solid particles suitable for intravenous delivery, the solid particles comprising a camptothecin, and a 0.3 nm to 3.0 mu m thick layer of a membrane-forming amphipathic lipid | SUPER GEN, INC. | 2003-03-18 | — | — | US | claimed |
| US-6509027-B2 | Anticancer agent | SUPERGEN, INC. | 2003-01-21 | — | — | US | claimed |
| EP-1270579-A1 | PROCESS FOR PRODUCING CAMPTOTHECIN | Kabushiki Kaisha Yakult Honsha (JP) | 2003-01-02 | — | — | EP | claimed |
| US-6497896-B2 | AQUEOUS SUSPENSION; THERMAL STERILIZATION | SUPERGEN, INC. | 2002-12-24 | — | — | US | claimed |
| US-20020150615-A1 | Injectable pharmaceutical composition comprising microdroplets of a camptothecin | SKYEPHARMA AG (CH) | 2002-10-17 | — | — | US | claimed |
| US-20020146460-A1 | Method for administering camptothecins VIA injection of pharmaceutical composition comprising coated particles of a camptothecin | ASTEX PHARMACEUTICALS, INC. | 2002-10-10 | — | — | US | claimed |
| US-20020147202-A1 | Method for administering camptothecins via injection of a pharmaceutical composition comprising microdroplets containing a camptothecin | RTP PHARMA INC. (CA) | 2002-10-10 | — | — | US | claimed |
| US-20020142048-A1 | Injectable pharmaceutical composition comprising coated particles of camptothecin | ASTEX PHARMACEUTICALS, INC. | 2002-10-03 | — | — | US | claimed |
| WO-2002064064-A1 | INJECTABLE PHARMACEUTICAL COMPOSITION COMPRISING MICROPARTICLES OR MICRODROPLETS OF CAMPTOTHECIN | SUPERGEN, INC. (US) | 2002-08-22 | — | — | WO | claimed |
| WO-2002000168-A2 | COMBINATION HIV THERAPY INCLUDING CAMPTOTHECIN | SUPERGEN, INC. (US) | 2002-01-03 | — | — | WO | claimed |