Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 18/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.80 |
| ▸ | GLA | P06280 | 3/20 | 0.80 |
| ▸ | RECQL | P46063 | 2/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.79 |
| ▸ | RAB9A | P51151 | 2/20 | 0.79 |
| ▸ | BLM | P54132 | 2/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.74 |
| ▸ | ACHE | P22303 | 1/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.74 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29994151 | 1.00 | TOP1 (1.00) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL1004508 | 1.00 | TOP1 (1.00) | TOP1ALDH1A1GLARECQLTDP1 | |
| Hydrochloric Acid SCHEMBL28012447 | 0.98 | TOP1 (0.97) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL17897650 | 0.92 | TOP1 (0.85) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL25932513 | 0.92 | TOP1 (0.85) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL10636628 | 0.91 | TOP1 (0.84) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL1006662 | 0.90 | TOP1 (1.00) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL27561956 | 0.90 | TOP1 (1.00) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL27367949 | 0.89 | TOP1 (0.81) | TOP1ALDH1A1GLARECQLTDP1 | |
| SCHEMBL23270615 | 0.89 | TOP1 (1.00) | TOP1ALDH1A1GLARECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343944-A | Gene, protein, recombinant vector and method for catalyzing synthesis of 9-methoxy camptothecine | 上海师范大学 | 2024-01-05 | — | — | CN | claimed |
| CN-107760737-A | A kind of method that high purity medical plant monomer camptothecine is extracted from mappia foetida | 恩施州地壹嘉知识产权服务有限公司 | 2018-03-06 | — | — | CN | claimed |
| CN-104619322-A | ANTICANCER PHARMACEUTICAL COMPOSITION, PREPARATION METHOD FOR SAME, AND USE THEREOF | ZHANG YUANJIN | 2015-05-13 | — | — | CN | claimed |
| CN-117343944-A | Gene, protein, recombinant vector and method for catalyzing synthesis of 9-methoxy camptothecine | 上海师范大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-117343944-A | Gene, protein, recombinant vector and method for catalyzing synthesis of 9-methoxy camptothecine | 上海师范大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-107760737-A | A kind of method that high purity medical plant monomer camptothecine is extracted from mappia foetida | 恩施州地壹嘉知识产权服务有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-104619322-A | ANTICANCER PHARMACEUTICAL COMPOSITION, PREPARATION METHOD FOR SAME, AND USE THEREOF | ZHANG YUANJIN | 2015-05-13 | — | — | CN | disclosed |
| CN-102051393-A | Method for extracting camptothecin and 9-methoxyl camptothecin from root-bark of pittosporumlike nothapodytes | ENSHI JINHUA BIO ENGINEERING CO LTD | 2011-05-11 | — | — | CN | disclosed |
| CN-102051393-A | Method for extracting camptothecin and 9-methoxyl camptothecin from root-bark of pittosporumlike nothapodytes | ENSHI JINHUA BIO ENGINEERING CO LTD | 2011-05-11 | — | — | CN | disclosed |