Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 18/20 | 0.81 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | GLA | P06280 | 3/20 | 0.71 |
| ▸ | RECQL | P46063 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | BLM | P54132 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | HBB | P68871 | 2/20 | 0.68 |
| ▸ | CASP1 | P29466 | 1/20 | 0.68 |
| ▸ | CASP7 | P55210 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | STAT6 | P42226 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484231 | 0.91 | TOP1 (0.79) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27595211 | 0.91 | TOP1 (0.79) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7262467 | 0.91 | TOP1 (0.79) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8483239 | 0.90 | TOP1 (0.77) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4272312 | 0.90 | TOP1 (0.77) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1004508 | 0.89 | TOP1 (1.00) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29994151 | 0.89 | TOP1 (1.00) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27827045 | 0.89 | TOP1 (1.00) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28751378 | 0.89 | TOP1 (0.74) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18251452 | 0.89 | TOP1 (0.80) | TOP1MEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073626-A2 | ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS | NUVATION BIO INC. (US) | 2024-04-04 | — | — | WO | disclosed |