SCHEMBL10045602

SCHEMBL10045602

Cc1nc2cc3scnc3cc2s1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.61
NPC1 O15118 5/20 0.61
RAB9A P51151 5/20 0.61
ALDH1A1 P00352 3/20 0.61
HSD17B10 Q99714 2/20 0.61
HPGD P15428 2/20 0.61
TP53 P04637 1/20 0.61
MAPT P10636 1/20 0.61
PKM P14618 1/20 0.61
GAA P10253 2/20 0.57
TDP1 Q9NUW8 4/20 0.44
ALOX15 P16050 1/20 0.42
ATM Q13315 1/20 0.42
CHRNB2 P17787 1/20 0.41
CHRNA4 P43681 1/20 0.41
HTT P42858 1/20 0.40
CLK1 P49759 1/20 0.40
CLK2 P49760 1/20 0.40
CLK3 P49761 1/20 0.40
KDM4E B2RXH2 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4384430 0.83 SMN1; SMN2 (0.85) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL3306481 0.81 SMN1; SMN2 (0.47) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL4296143 0.78 ALDH1A1 (0.52) NPC1RAB9AALDH1A1HSD17B10TDP1
SCHEMBL13801957 0.77 NPC1 (0.40) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL19268435 0.77 NPC1 (0.41) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL12635465 0.77 SMN1; SMN2 (1.00) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL21166567 0.74 SMN1; SMN2 (0.68) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL30093444 0.73 GAA (0.45) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL30422583 0.73 GAA (1.00) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL4048510 0.73 GAA (0.45) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11209732-B2 Near infrared absorbing composition, film, infrared cut filter, solid image pickup element, infrared absorber, and compound FUJIFILM CORPORATION (JP) 2021-12-28 US disclosed
US-8471019-B2 Quinoid systems as organic semiconductors BASF SE (DE) 2013-06-25 US disclosed
US-8101776-B2 Organic semiconductors and their manufacture BASF SE (DE) 2012-01-24 US disclosed
US-20110017981-A1 PROCESS FOR THE PREPARATION OF SEMICONDUCTING LAYERS BASF SE (US) 2011-01-27 US disclosed
US-20090299070-A1 Organic Semiconductors and Their Manufacture CLAP CO., LTD. (KR) 2009-12-03 US disclosed
US-20090261321-A1 Quinoid Systems as Organic Semiconductors CIBA CORPORATION (US) 2009-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090261321-A1 Quinoid Systems as Organic Semiconductors HRH4, HRH3, H1-0 SMN1; SMN2 4242/4885NPC1 3945/4885RAB9A 1996/4885
US-11209732-B2 Near infrared absorbing composition, film, infrared cut filter, solid image pickup element, infrared absorber, and compound ASH2L, RFT1, STRA6 SMN1; SMN2 2208/4885NPC1 483/4885RAB9A 4002/4885
US-20090299070-A1 Organic Semiconductors and Their Manufacture YBX1, CDYL, PROX1 SMN1; SMN2 1169/4885NPC1 4869/4885RAB9A 4601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.