SCHEMBL4048510

SCHEMBL4048510

Cc1cc2ncsc2cc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.45
ALDH1A1 P00352 5/20 0.43
HSD17B10 Q99714 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
KDM4E B2RXH2 2/20 0.41
HKDC1 Q2TB90 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
DYRK1A Q13627 1/20 0.39
MAPK1 P28482 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
STIM1 Q13586 1/20 0.36
ORAI1 Q96D31 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30093444 1.00 GAA (0.45) GAAALDH1A1HSD17B10SMN1; SMN2TP53
SCHEMBL2999828 0.83 TERT (0.45) GAAALDH1A1HSD17B10SMN1; SMN2TP53
SCHEMBL12121770 0.83 TGFBR1 (0.44) ALDH1A1HSD17B10SMN1; SMN2NPC1RAB9A
SCHEMBL30089784 0.83 ALDH1A1 (0.38) GAAALDH1A1HSD17B10SMN1; SMN2NPC1
SCHEMBL4052274 0.83 RIPK2 (0.39) GAAALDH1A1HSD17B10SMN1; SMN2NPC1
SCHEMBL720130 0.83 ALDH1A1 (0.38) GAAALDH1A1HSD17B10SMN1; SMN2NPC1
SCHEMBL5541837 0.83 NPC1 (0.41) ALDH1A1HSD17B10SMN1; SMN2NPC1RAB9A
SCHEMBL4075601 0.83 ALDH1A1 (0.38) GAAALDH1A1HSD17B10SMN1; SMN2NPC1
SCHEMBL22304452 0.83 DYRK1A (0.42) GAAALDH1A1HSD17B10SMN1; SMN2TP53
SCHEMBL6129384 0.83 ALDH1A1 (0.38) GAAALDH1A1HSD17B10SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 458 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115504942-A Synthesis method of alkyl or acyl substituted benzothiazole derivative 汕头大学 2022-12-23 CN claimed
US-5861424-A CATIONIC HETEROCYCLIC COMPOUNDS FOR TREATING CANCER DANA FARBER CANCER INSTITUTE (US) 1999-01-19 US claimed
EP-0368327-B1 Light-sensitive composition FUJI PHOTO FILM CO LTD (JP) 1995-02-15 EP claimed
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP claimed
US-5202221-A Photocrosslinkable copolymer having maleimido side chain, cyanine dye sensitizer FUJI PHOTO FILM CO., LTD. (JP) 1993-04-13 US claimed
US-4891305-A LASERS RICOH CO., LTD. (JP) 1990-01-02 US claimed
US-4889796-A CONTAINING BENZOXAZOLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1989-12-26 US claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed
CN-117658945-A Synthesis method of persulfate-induced alkylation modified nitrogen heterocyclic compound 浙江工业大学 2024-03-08 CN disclosed
US-20230303552-A1 ARYLSULFONYL DERIVATIVES AND THEIR USE AS MUSCARINIC ACETYLCHOLINE RECEPTOR M5 INHIBITORS VANDERBILT UNIVERSITY 2023-09-28 US disclosed
EP-4209485-A1 COMPOUND HAVING ANTITUMOR ACTIVITY AND USE THEREOF Innovstone Therapeutics Limited (CN) 2023-07-12 EP disclosed
US-20230203048-A1 SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2023-06-29 US disclosed
CN-116332870-A Method for preparing 2-substituted benzothiazoline compounds by photocatalysis 浙江工业大学台州研究院 2023-06-27 CN disclosed
US-3953215-A X-RAY FILM FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 US disclosed
US-3951666-A CYANINE AND MEROCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-04-20 US disclosed
US-3945832-A Fogged, direct-positive silver halide emulsion containing desensitizers and a dimethine optical sensitizing dye FUJI PHOTO FILM CO., LTD. (JA) 1976-03-23 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed
US-3931248-A Reactive high polymer compound FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203048-A1 SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS ACE, ACE2, PKD1 GAA 920/4885ALDH1A1 319/4885HSD17B10 900/4885
US-20230303552-A1 ARYLSULFONYL DERIVATIVES AND THEIR USE AS MUSCARINIC ACETYLCHOLINE RECEPTOR M5 INHIBITORS CHRM5, CHRM1, CHRM2 GAA 3814/4885ALDH1A1 557/4885HSD17B10 4502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.