Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.57 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 5/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL972712 | 0.79 | CALM1 (0.92) | CALM1SLC22A2LTA4HIDH1PLA2G10 | |
| SCHEMBL8094422 | 0.79 | CALM1 (0.92) | CALM1SLC22A2LTA4HIDH1PLA2G10 | |
| SCHEMBL5450 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL27978245 | 0.76 | CALM1 (0.86) | CALM1SLC22A2LTA4HIDH1PLA2G10 | |
| Diphenylmethane SCHEMBL14763944 | 0.76 | CALM1 (1.00) | CALM1SLC22A2LTA4HIDH1PLA2G10 | |
| Diphenylmethane SCHEMBL3792579 | 0.76 | CALM1 (1.00) | CALM1SLC22A2LTA4HIDH1PLA2G10 | |
| Diphenylmethane SCHEMBL4361124 | 0.76 | CALM1 (1.00) | CALM1SLC22A2LTA4HIDH1PLA2G10 | |
| Diphenylmethane SCHEMBL1303 | 0.76 | CALM1 (1.00) | CALM1SLC22A2LTA4HIDH1PLA2G10 | |
| Diphenylmethane SCHEMBL28172316 | 0.76 | CALM1 (1.00) | CALM1SLC22A2LTA4HIDH1PLA2G10 | |
| SCHEMBL10318927 | 0.74 | TSHR (0.39) | CALM1SLC22A2TRPA1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902252-B2 | Inhibitors of D-amino acid oxidase | SEPRACOR, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| WO-2011011330-A2 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20100029737-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029737-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | DDO, DAO, ACHE | CALM1 1005/4885SLC22A2 4376/4885LTA4H 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.