Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | S100B | P04271 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28756470 | 1.00 | CA2 (0.61) | CA2S100BALDH1A1MAPTKDM4E | |
| SCHEMBL1033697 | 1.00 | CA2 (0.61) | CA2S100BALDH1A1MAPTKDM4E | |
| SCHEMBL1033699 | 1.00 | CA2 (0.61) | CA2S100BALDH1A1MAPTKDM4E | |
| SCHEMBL12416601 | 0.89 | PTGS2 (0.67) | CA2S100BALDH1A1MAPTKDM4E | |
| SCHEMBL2455350 | 0.89 | PTGS2 (0.67) | CA2S100BALDH1A1MAPTKDM4E | |
| SCHEMBL15347676 | 0.89 | CA2 (0.71) | CA2S100BALDH1A1MAPTKDM4E | |
| SCHEMBL11320970 | 0.89 | CA2 (0.71) | CA2S100BALDH1A1MAPTKDM4E | |
| SCHEMBL2839684 | 0.89 | CA2 (0.71) | CA2S100BALDH1A1MAPTKDM4E | |
| SCHEMBL2455348 | 0.89 | PTGS2 (0.67) | CA2S100BALDH1A1MAPTKDM4E | |
| SCHEMBL20186948 | 0.89 | PTGS2 (0.67) | CA2S100BALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590940-B1 | NEW METHOD FOR PREPARING EZETIMIBE | MOEHS IBÉRICA S L (ES) | 2014-08-27 | — | — | EP | disclosed |
| WO-2012004382-A1 | NEW METHOD FOR PREPARING EZETIMIBE | MOEHS IBERICA S.L. (ES) | 2012-01-12 | — | — | WO | disclosed |
| US-8013150-B2 | Process for the preparation of ezetimibe | MSN LABORATORIES LTD. (IN) | 2011-09-06 | — | — | US | disclosed |
| US-20090048441-A1 | Process for the Preparation of Ezetimibe | MSN LABORATORIES LTD. (IN) | 2009-02-19 | — | — | US | disclosed |
| WO-2008032338-A2 | IMPROVED PROCESS FOR THE PREPARATION OF EZETIMIBE AND ITS INTERMEDIATES | SATYANARAYANA REDDY MANNE (IN) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048441-A1 | Process for the Preparation of Ezetimibe | APOB, PCSK9, HMGCR | CA2 3605/4885S100B 4400/4885ALDH1A1 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.