SCHEMBL10045765

SCHEMBL10045765

OC[C@H]1OC=CC(O)C1O

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FUCA1 P04066 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
LMNA P02545 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
LGALS8 O00214 4/20 0.32
LGALS1 P09382 2/20 0.32
LGALS3 P17931 2/20 0.32
LGALS9 O00182 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GBA1 P04062 1/20 0.31
CA12 O43570 2/20 0.31
CA9 Q16790 2/20 0.31
CA2 P00918 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13822005 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL154476 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL6534721 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL12205165 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL7948561 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL12921945 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL423526 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL20844917 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL22472219 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL31384230 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203087-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
US-20120016004-A1 COMPOSITIONS FOR INHIBITING GENE EXPRESSION AND USES THEREOF IDERA PHARMACEUTICALS, INC. 2012-01-19 US disclosed
WO-2010039137-A1 IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE IDERA PHARMACEUTICALS, INC. (US) 2010-04-08 WO disclosed
WO-2009014887-A2 STABILIZED IMMUNE MODULATORY RNA (SIMRA) COMPOUNDS IDERA PHARMACEUTICALS, INC. (US) 2009-01-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120016004-A1 COMPOSITIONS FOR INHIBITING GENE EXPRESSION AND USES THEREOF RNGTT, NSUN2, RTCB FUCA1 642/4885L3MBTL1 11/4885ALDH1A1 2452/4885
US-20230203087-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF RNGTT, NSUN2, ALKBH1 FUCA1 457/4885L3MBTL1 490/4885ALDH1A1 1901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.