SCHEMBL7948561

SCHEMBL7948561

OCC1OC=CC(O)C1O

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FUCA1 P04066 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
LMNA P02545 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
LGALS8 O00214 4/20 0.32
LGALS1 P09382 2/20 0.32
LGALS3 P17931 2/20 0.32
LGALS9 O00182 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GBA1 P04062 1/20 0.31
CA12 O43570 2/20 0.31
CA9 Q16790 2/20 0.31
CA2 P00918 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13822005 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL154476 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL6534721 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL10045765 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL12205165 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL12921945 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL423526 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL20844917 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL22472219 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA
SCHEMBL31384230 1.00 FUCA1 (0.52) FUCA1L3MBTL1ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083851-A1 POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS AVILAR THERAPEUTICS, INC. (US) 2026-03-26 US disclosed
WO-2024098039-A2 POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS AVILAR THERAPEUTICS, INC. (US) 2024-05-10 WO disclosed
US-20240072809-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2024-02-29 US disclosed
US-11819551-B2 ASGPR-binding compounds for the degradation of extracellular proteins AVILAR THERAPEUTICS, INC. (US) 2023-11-21 US disclosed
US-20230346905-A1 PENTAVALENT VACCINE AGAINST NEISSERIA MENINGITIDIS COMPRISING A SYNTHETIC MEN A ANTIGEN GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-11-02 US disclosed
US-20230346905-A1 PENTAVALENT VACCINE AGAINST NEISSERIA MENINGITIDIS COMPRISING A SYNTHETIC MEN A ANTIGEN GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-11-02 US disclosed
US-20230203484-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
US-20230203484-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
US-20230203087-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
EP-4200022-A1 TRIPTOLIDE CONJUGATES AND USES THEREOF Reyoung Corporation (US) 2023-06-28 EP disclosed
WO-2009018431-A2 NOVEL SYNTHETIC AGONISTS OF TLR9 IDERA PHARMACEUTICALS, INC. (US) 2009-02-05 WO disclosed
US-20080171712-A1 At least two oligonucleotides having modified purine bases, such as deazaguanosines or deaza-adenosines, linked by an alkyl or phenolic diol or triol; vaccines, DNA vaccines; anticarcinogenic, antiallergenic, antiinflammatory agents; bronchodilators IDERA PHARMACEUTICALS, INC. 2008-07-17 US disclosed
US-20080089883-A1 IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE IDERA PHARMACEUTICALS, INC. 2008-04-17 US disclosed
US-7338940-B2 Cancer treatment including glycolytic inhibitors LAMPIDIS THEODORE J 2008-03-04 US disclosed
US-7338940-B2 Cancer treatment including glycolytic inhibitors LAMPIDIS THEODORE J 2008-03-04 US disclosed
US-7335500-B2 Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose THE SCRIPPS RESEARCH INSTITUTE (US) 2008-02-26 US disclosed
US-7335500-B2 Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose THE SCRIPPS RESEARCH INSTITUTE (US) 2008-02-26 US disclosed
WO-2008007153-A2 ANTIVIRAL COMPOUNDS IQUR LTD. (GB) 2008-01-17 WO disclosed
US-7160865-B2 Heterocyclic alcohols such as 2-deoxy-D-glucose or 5-thio-D-glucose, used as anticarcinogenic agents or angiogenesis inhibitors; glycolysis antagonists LAMPIDIS THEODORE J 2007-01-09 US disclosed
US-7160865-B2 Heterocyclic alcohols such as 2-deoxy-D-glucose or 5-thio-D-glucose, used as anticarcinogenic agents or angiogenesis inhibitors; glycolysis antagonists LAMPIDIS THEODORE J 2007-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11819551-B2 ASGPR-binding compounds for the degradation of extracellular proteins ASGR1, ENGASE, FCGR2A FUCA1 24/4885L3MBTL1 2804/4885ALDH1A1 3319/4885
US-20080089883-A1 IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE TLR3, TLR9, TLR5 FUCA1 1492/4885L3MBTL1 1268/4885ALDH1A1 4183/4885
US-20260083851-A1 POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS ASGR1, FCGR2A, FCGR3B FUCA1 139/4885L3MBTL1 1884/4885ALDH1A1 2349/4885
US-20230203087-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF RNGTT, NSUN2, ALKBH1 FUCA1 457/4885L3MBTL1 490/4885ALDH1A1 1901/4885
US-20080171712-A1 At least two oligonucleotides having modified purine bases, such as deazaguanosines or deaza-adenosines, linked by an alkyl or phenolic diol or triol; vaccines, DNA vaccines; anticarcinogenic, antiallergenic, antiinflammatory agents; bronchodilators TLR8, TLR7, TLR9 FUCA1 2338/4885L3MBTL1 1561/4885ALDH1A1 1872/4885
US-20230346905-A1 PENTAVALENT VACCINE AGAINST NEISSERIA MENINGITIDIS COMPRISING A SYNTHETIC MEN A ANTIGEN MEN1, KLK3, NASP FUCA1 2788/4885L3MBTL1 1170/4885ALDH1A1 4850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.