Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689377 | 0.83 | MAPT (0.46) | RAB9AALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL18439178 | 0.78 | MAPT (0.55) | RAB9AALDH1A1HPGDTLR8NPC1 | |
| SCHEMBL10207559 | 0.77 | RAB9A (0.62) | RAB9AALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL2336139 | 0.77 | HTR7 (0.56) | RAB9AALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL225789 | 0.76 | GSTP1 (0.58) | RAB9AALDH1A1NPC1SMN1; SMN2MAPK1 | |
| SCHEMBL13983281 | 0.75 | MAPT (0.48) | RAB9AALDH1A1HPGDNPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL514849 | 0.75 | RAB9A (0.59) | RAB9AALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL14038420 | 0.74 | MAPT (0.55) | RAB9AALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL12758744 | 0.74 | MAPT (0.52) | RAB9AALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL11188343 | 0.74 | HTR7 (0.54) | RAB9AALDH1A1NPC1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323982-B1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | UNIV GEORGETOWN (US) | 2012-02-29 | — | — | EP | disclosed |
| US-20110152339-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | GEORGETOWN UNIVERSITY | 2011-06-23 | — | — | US | disclosed |
| US-20100130579-A1 | CANCER THERAPY | GEORGETOWN UNIVERSITY (US) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152339-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | RASSF5, RASSF2, MKI67 | RAB9A 648/4885ALDH1A1 830/4885HPGD 2522/4885 |
| US-20100130579-A1 | CANCER THERAPY | RASSF5, RASSF2, DNMT1 | RAB9A 1659/4885ALDH1A1 227/4885HPGD 1691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.