Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7251545 | 0.84 | PTGES (0.57) | MAPTMEN1KMT2ARAB9APTGES | |
| SCHEMBL9314457 | 0.84 | RAB9A (0.58) | MAPTMEN1KMT2ARAB9AABCB1 | |
| SCHEMBL10046155 | 0.83 | RAB9A (0.48) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL18487331 | 0.81 | C5AR1 (0.47) | MAPTABCB1MRGPRX4FFAR1MAPK1 | |
| SCHEMBL7250438 | 0.79 | PTGES (0.57) | MAPTMEN1KMT2ARAB9APTGES | |
| SCHEMBL30189830 | 0.79 | KMT2A (0.53) | MAPTMEN1KMT2ARAB9AABCB1 | |
| SCHEMBL3926941 | 0.79 | KMT2A (0.53) | MAPTMEN1KMT2ARAB9AABCB1 | |
| SCHEMBL7251777 | 0.78 | PTGES (0.60) | MAPTMEN1KMT2ARAB9APTGES | |
| SCHEMBL7005180 | 0.77 | KMT2A (0.59) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL1031014 | 0.77 | PTGES (0.49) | MAPTMEN1KMT2ARAB9APTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10457639-B2 | Fluorescent regulators of RASSF1A expression and human cancer cell proliferation | GEORGETOWN UNIVERSITY (US) | 2019-10-29 | — | — | US | disclosed |
| EP-2484666-A1 | Fluorescent regulators of RASSF1A expression and human cancer cell proliferation | Georgetown University (US) | 2012-08-08 | — | — | EP | disclosed |
| EP-2323982-B1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | UNIV GEORGETOWN (US) | 2012-02-29 | — | — | EP | disclosed |
| US-20110152339-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | GEORGETOWN UNIVERSITY | 2011-06-23 | — | — | US | disclosed |
| EP-2323982-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | Georgetown University (US) | 2011-05-25 | — | — | EP | disclosed |
| US-20100130579-A1 | CANCER THERAPY | GEORGETOWN UNIVERSITY (US) | 2010-05-27 | — | — | US | disclosed |
| WO-2010019271-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | GEORGETOWN UNIVERSITY (US) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152339-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | RASSF5, RASSF2, MKI67 | MAPT 4658/4885MEN1 3506/4885KMT2A 454/4885 |
| US-20100130579-A1 | CANCER THERAPY | RASSF5, RASSF2, DNMT1 | MAPT 3975/4885MEN1 2048/4885KMT2A 37/4885 |
| US-10457639-B2 | Fluorescent regulators of RASSF1A expression and human cancer cell proliferation | RASSF5, RASSF2, MKI67 | MAPT 4658/4885MEN1 3506/4885KMT2A 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.