Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12980779 | 1.00 | KDM4E (0.38) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20993534 | 0.97 | KDM4E (0.38) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12981410 | 0.88 | TSHR (0.39) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12307356 | 0.88 | KDM4E (0.36) | KDM4EALDH1A1MEN1KMT2ANCF1 | |
| SCHEMBL24092208 | 0.88 | KDM4E (0.32) | KDM4EALDH1A1 | |
| SCHEMBL20993448 | 0.88 | GLP1R (0.37) | KDM4EALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL4402902 | 0.87 | KDM4E (0.43) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL20133152 | 0.87 | KDM4E (0.43) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL20128726 | 0.87 | KDM4E (0.43) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL27408407 | 0.87 | KDM4E (0.43) | KDM4EALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3773750-B1 | FORMULATION AND METHOD OF PREPARATION | GE HEALTHCARE AS (NO) | 2022-04-20 | — | — | EP | disclosed |
| WO-2019185607-A1 | FORMULATION AND METHOD OF PREPARATION | GE HEALTHCARE AS (NO) | 2019-10-03 | — | — | WO | disclosed |
| EP-2643023-B1 | RADIOIODINATION METHOD | GE HEALTHCARE LTD (GB) | 2018-07-18 | — | — | EP | disclosed |
| EP-2795317-B1 | Composition for use in a method for cancer selection | GE HEALTHCARE LTD (GB) | 2018-05-30 | — | — | EP | disclosed |
| US-9956303-B2 | Anti-met therapy for previously diagnosed cancer patients | GE HEALTHCARE LIMITED (GB) | 2018-05-01 | — | — | US | disclosed |
| EP-2680888-B1 | TECHNETIUM LABELLED PEPTIDES | GE HEALTHCARE LTD (GB) | 2017-10-18 | — | — | EP | disclosed |
| EP-2467365-B1 | RADIOIODINATION METHOD | GE HEALTHCARE LTD (GB) | 2017-08-09 | — | — | EP | disclosed |
| EP-2605802-B1 | PEPTIDE RADIOTRACER COMPOSITIONS | GE HEALTHCARE LTD (GB) | 2017-04-26 | — | — | EP | disclosed |
| EP-2509638-B1 | IODINE RADIOLABELLING METHOD | GE HEALTHCARE LTD (GB) | 2017-04-19 | — | — | EP | disclosed |
| US-20120251447-A1 | RADIOIODINATED TROPANE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2012-10-04 | — | — | US | disclosed |
| US-20110280806-A1 | DYE CONJUGATE IMAGING AGENTS | GE HEALTHCARE AS (NO) | 2011-11-17 | — | — | US | disclosed |
| US-20100196282-A1 | OPTICAL IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120251447-A1 | RADIOIODINATED TROPANE DERIVATIVES | ADRB3, TH, TBXA2R | KDM4E 3479/4885ALDH1A1 834/4885MEN1 2181/4885 |
| US-20110280806-A1 | DYE CONJUGATE IMAGING AGENTS | DSC1, SDCBP, DOCK5 | KDM4E 3469/4885ALDH1A1 1716/4885MEN1 804/4885 |
| US-20100196282-A1 | OPTICAL IMAGING AGENTS | VIP, SSTR4, NGLY1 | KDM4E 3923/4885ALDH1A1 3887/4885MEN1 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.