SCHEMBL4402902

SCHEMBL4402902

CC(C)(C)NCCOCCOCC(=O)C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.43
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GAA P10253 2/20 0.35
CES2 O00748 1/20 0.33
POLB P06746 1/20 0.33
MAPK1 P28482 2/20 0.31
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20128726 1.00 KDM4E (0.43) KDM4EALDH1A1MEN1KMT2AGAA
SCHEMBL20133152 1.00 KDM4E (0.43) KDM4EALDH1A1MEN1KMT2AGAA
SCHEMBL27408407 1.00 KDM4E (0.43) KDM4EALDH1A1MEN1KMT2AGAA
SCHEMBL4547565 0.96 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AGAA
SCHEMBL20993534 0.91 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AGAA
SCHEMBL20234227 0.89 KDM4E (0.37) KDM4EALDH1A1MEN1KMT2AGAA
SCHEMBL21316648 0.87 KDM4E (0.42) KDM4EALDH1A1MEN1KMT2AGAA
SCHEMBL12980779 0.87 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AGAA
SCHEMBL10046329 0.87 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AGAA
SCHEMBL23483122 0.86 MEN1 (0.33) KDM4EALDH1A1MEN1KMT2ACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239863-A1 GIP RECEPTOR AGONIST AND USE THEREOF HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO., LTD. (CN) 2024-07-18 US disclosed
US-20240239863-A1 GIP RECEPTOR AGONIST AND USE THEREOF HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO., LTD. (CN) 2024-07-18 US disclosed
US-20240209439-A1 NUCLEOTIDE ANALOGUE FOR SEQUENCING BGI SHENZHEN (CN) 2024-06-27 US disclosed
US-20240209028-A1 CNP COMPOUNDS NOVO NORDISK A/S (DK) 2024-06-27 US disclosed
US-12018057-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases JANSSEN BIOTECH, INC. (US) 2024-06-25 US disclosed
US-12018057-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases JANSSEN BIOTECH, INC. (US) 2024-06-25 US disclosed
WO-2024094747-A1 CNP COMPOUNDS NOVO NORDISK A/S (DK) 2024-05-10 WO disclosed
US-20230357199-A1 ARYL, HETEROARYL, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS ACHILLION PHARMACEUTICALS, INC. 2023-11-09 US disclosed
US-20230357199-A1 ARYL, HETEROARYL, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS ACHILLION PHARMACEUTICALS, INC. 2023-11-09 US disclosed
US-11753443-B2 Conjugated hepcidin mimetics PROTAGONIST THERAPEUTICS, INC. (US) 2023-09-12 US disclosed
US-20110213131-A1 Method of Acylating a Peptide or Protein NOVO NORDISK A/S (DK) 2011-09-01 US disclosed
US-20100317057-A1 SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES NOVO NORDISK A/S (DK) 2010-12-16 US disclosed
US-20100179304-A1 Somatostatin-Dopamine Chimeric analogs IPSEN PHARMA S.A.S. (FR) 2010-07-15 US disclosed
US-20100179304-A1 Somatostatin-Dopamine Chimeric analogs IPSEN PHARMA S.A.S. (FR) 2010-07-15 US disclosed
US-20090275501-A1 Somatostatin-dopamine chimeric analogs IPSEN PHARMA S.A.S. (FR) 2009-11-05 US disclosed
US-20090275501-A1 Somatostatin-dopamine chimeric analogs IPSEN PHARMA S.A.S. (FR) 2009-11-05 US disclosed
US-7579435-B2 Somatostatin-dopamine chimeric analogs SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) 2009-08-25 US disclosed
US-7579435-B2 Somatostatin-dopamine chimeric analogs SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) 2009-08-25 US disclosed
US-7572883-B2 Somatostatin-dopamine chimeric analogs SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) 2009-08-11 US disclosed
US-7572883-B2 Somatostatin-dopamine chimeric analogs SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) 2009-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240209439-A1 NUCLEOTIDE ANALOGUE FOR SEQUENCING NT5C3B, NT5E, NUDT1 KDM4E 2062/4885ALDH1A1 1433/4885MEN1 1993/4885
US-20240209028-A1 CNP COMPOUNDS NPPA, NPR1, NPR3 KDM4E 4814/4885ALDH1A1 4267/4885MEN1 1316/4885
US-20230357199-A1 ARYL, HETEROARYL, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS CFD, TFPI, CFH KDM4E 3553/4885ALDH1A1 2338/4885MEN1 1035/4885
US-20100179304-A1 Somatostatin-Dopamine Chimeric analogs SSTR3, SLC6A3, PRLHR KDM4E 3745/4885ALDH1A1 2606/4885MEN1 1131/4885
US-11753443-B2 Conjugated hepcidin mimetics HAMP, VIP, HDGF KDM4E 4176/4885ALDH1A1 3616/4885MEN1 277/4885
US-20110213131-A1 Method of Acylating a Peptide or Protein DNPEP, PTMA, ANPEP KDM4E 4619/4885ALDH1A1 3829/4885MEN1 2834/4885
US-20240239863-A1 GIP RECEPTOR AGONIST AND USE THEREOF GIPR, GLP1R, GPR119 KDM4E 3791/4885ALDH1A1 4748/4885MEN1 1431/4885
US-12018057-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases IL23R, IL1RN, VIP KDM4E 4705/4885ALDH1A1 4574/4885MEN1 3503/4885
US-20090275501-A1 Somatostatin-dopamine chimeric analogs SSTR3, SLC6A3, PRLHR KDM4E 3745/4885ALDH1A1 2606/4885MEN1 1131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.