Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI | P10646 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
| ▸ | IL23R | Q5VWK5 | 10/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23057565 | 0.87 | IL23R (0.51) | TFPIOPRL1IL23R | |
| SCHEMBL10046542 | 0.87 | IL23R (0.51) | TFPIOPRL1IL23R | |
| SCHEMBL31181296 | 0.86 | IL23R (0.48) | TFPIOPRL1IL23RKEAP1 | |
| SCHEMBL31181281 | 0.86 | IL23R (0.50) | TFPIOPRL1IL23RKEAP1 | |
| SCHEMBL16349703 | 0.86 | IL23R (0.50) | TFPIOPRL1IL23R | |
| SCHEMBL12082890 | 0.86 | IL23R (0.50) | TFPIOPRL1IL23R | |
| SCHEMBL20809945 | 0.85 | IL23R (0.52) | IL23R | |
| SCHEMBL22382220 | 0.84 | IL23R (0.51) | OPRL1IL23R | |
| SCHEMBL13703199 | 0.84 | IL23R (0.51) | OPRL1IL23R | |
| SCHEMBL22003315 | 0.84 | IL23R (0.48) | TFPIOPRL1IL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299030-B2 | Peptide-based compounds | GE HEALTHCARE LIMITED (GB) | 2012-10-30 | — | — | US | disclosed |
| US-20120020882-A1 | PEPTIDE-BASED COMPOUNDS | GE HEALTHCARE AS (NO) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120020882-A1 | PEPTIDE-BASED COMPOUNDS | ITGB3, ITGAV, SELPLG | TFPI 717/4885OPRL1 541/4885IL23R 973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.