Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046494 | 0.82 | GAA (0.56) | GAAALDH1A1HTTLMNAMEN1 | |
| SCHEMBL10046482 | 0.81 | GAA (0.51) | GAAALDH1A1HTTLMNAMEN1 | |
| SCHEMBL10046492 | 0.80 | GAA (0.46) | GAAALDH1A1HTTLMNAMEN1 | |
| SCHEMBL325499 | 0.79 | GPR174 (0.57) | GAAALDH1A1HTTLMNAMEN1 | |
| SCHEMBL10046487 | 0.77 | GAA (0.73) | GAAALDH1A1HTTLMNAMEN1 | |
| SCHEMBL14904060 | 0.77 | GAA (0.51) | GAAALDH1A1HTTLMNAMEN1 | |
| SCHEMBL15057514 | 0.76 | ATM (0.48) | GAAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL30545905 | 0.67 | GPR174 (0.75) | GAAALDH1A1HTTLMNAMEN1 | |
| SCHEMBL7820721 | 0.67 | GPR174 (0.75) | GAAALDH1A1HTTLMNAMEN1 | |
| SCHEMBL9223540 | 0.67 | ALOX5 (0.55) | GAAMEN1KMT2AL3MBTL1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906416-B2 | Xanthenedione derivatives for the treatment of pigmentation and skin ageing disorders | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2014-12-09 | — | — | US | disclosed |
| US-8906416-B2 | Xanthenedione derivatives for the treatment of pigmentation and skin ageing disorders | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2014-12-09 | — | — | US | disclosed |
| US-20130108568-A1 | XANTHENEDIONE DERIVATIVES FOR THE TREATMENT OF PIGMENTATION AND SKIN AGEING DISORDERS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-05-02 | — | — | US | disclosed |
| US-20130108568-A1 | XANTHENEDIONE DERIVATIVES FOR THE TREATMENT OF PIGMENTATION AND SKIN AGEING DISORDERS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-05-02 | — | — | US | disclosed |
| US-20130108568-A1 | XANTHENEDIONE DERIVATIVES FOR THE TREATMENT OF PIGMENTATION AND SKIN AGEING DISORDERS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-05-02 | — | — | US | disclosed |
| WO-2012004390-A1 | XANTHENEDIONE DERIVATIVES FOR THE TREATMENT OF PIGMENTATION AND SKIN AGEING DISORDERS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130108568-A1 | XANTHENEDIONE DERIVATIVES FOR THE TREATMENT OF PIGMENTATION AND SKIN AGEING DISORDERS | ACOX3, CBR3, GALR3 | GAA 1289/4885ALDH1A1 1099/4885HTT 987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.