Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11812965 | 0.90 | KDM4C (0.33) | KDM4CNPC1RAB9AGRM5MEN1 | |
| SCHEMBL6167587 | 0.87 | KDM4C (0.33) | KDM4CNPC1RAB9AGRM5MEN1 | |
| SCHEMBL10576592 | 0.87 | MEN1 (0.38) | KDM4CNPC1RAB9AGRM5MEN1 | |
| SCHEMBL9309065 | 0.86 | KDM4C (0.32) | KDM4CNPC1RAB9AGRM5GCK | |
| SCHEMBL6335488 | 0.84 | MEN1 (0.35) | KDM4CNPC1RAB9AGRM5MEN1 | |
| SCHEMBL10560537 | 0.82 | MEN1 (0.41) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL1227411 | 0.82 | MEN1 (0.34) | KDM4CNPC1RAB9AGRM5MEN1 | |
| SCHEMBL6607902 | 0.82 | MEN1 (0.32) | KDM4CNPC1RAB9AGRM5MEN1 | |
| SCHEMBL6535768 | 0.82 | KDM4C (0.31) | KDM4CNPC1RAB9AGRM5 | |
| SCHEMBL11813613 | 0.81 | MEN1 (0.35) | KDM4CNPC1RAB9AGRM5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902252-B2 | Inhibitors of D-amino acid oxidase | SEPRACOR, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| US-7902252-B2 | Inhibitors of D-amino acid oxidase | SEPRACOR, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| WO-2011011330-A2 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20100029737-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2010-02-04 | — | — | US | disclosed |
| US-20100029737-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2010-02-04 | — | — | US | disclosed |
| US-6867161-B1 | Titanium catalyst and organotitanium reacting reagent, production thereof, and reaction thereby | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-03-15 | — | — | US | disclosed |
| EP-0820809-A1 | TITANIUM CATALYST, ORGANOTITANIUM REACTION REAGENT, PROCESSES FOR PRODUCING THESE, AND METHOD OF REACTION USING THESE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-4477388-A | CHEMICAL INTERMEDIATES FOR PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1984-10-16 | — | — | US | disclosed |
| US-4390711-A | 16-Hydroxy-5-iodo-prostacyclin analogs of the 1 series | AMERICAN CYANAMID COMPANY (US) | 1983-06-28 | — | — | US | disclosed |
| EP-0052204-A1 | Prostacyclin analogs of the 1 series and related analogs | AMERICAN CYANAMID COMPANY (US) | 1982-05-26 | — | — | EP | disclosed |
| US-4172839-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4170597-A | 1-Hydroxymethyl-1-oxo-prostane derivatives of the E2 series | AMERICAN CYANAMID COMPANY (US) | 1979-10-09 | — | — | US | disclosed |
| US-4165331-A | PROSTAGLANDINS/AND DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| EP-0002590-A1 | Novel prostaglandin compounds, processes for the preparation thereof and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |
| US-4154959-A | 11-(2-Hydroxyethylthio)prostenoic acid E series derivatives | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4154954-A | BRONCHODILATOR AGENTS; ANTIINFLAMMATORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4113967-A | BRONCHODILATORS, HYPOTENSIVE, ANTISECRETORY | AMERICAN CYANAMID COMPANY (US) | 1978-09-12 | — | — | US | disclosed |
| US-4111959-A | BRONCHODILATORS, ANTIINFLAMMATORY, HYPOTENSIVE, ANTISECRETORY | AMERICAN CYANAMID COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4085272-A | BRONCHODILATORS, INFLAMMATORY MEDEATOR RELEASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4064350-A | 15,16-Dihydroxyprostaglandins | G. D. SEARLE & CO. (US) | 1977-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029737-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | DDO, DAO, ACHE | KDM4C 2902/4885NPC1 4329/4885RAB9A 2295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.