Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14286145 | 0.86 | HRH3 (0.33) | SMN1; SMN2CHRM1DRD2HRH1CHRM2 | |
| SCHEMBL12181600 | 0.83 | SMN1; SMN2 (0.35) | SMN1; SMN2CHRM1DRD2HRH1CHRM2 | |
| SCHEMBL13510585 | 0.82 | MAPT (0.36) | SMN1; SMN2CHRM1DRD2HRH1CHRM2 | |
| SCHEMBL10015644 | 0.80 | CHRM1 (0.45) | SMN1; SMN2CHRM1DRD2HRH1CHRM2 | |
| SCHEMBL420320 | 0.78 | CHRM1 (0.46) | SMN1; SMN2CHRM1DRD2HRH1CHRM2 | |
| SCHEMBL10036917 | 0.77 | HRH1 (0.45) | SMN1; SMN2CHRM1DRD2HRH1CHRM2 | |
| SCHEMBL13160756 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2CHRM1DRD2HRH1CHRM2 | |
| SCHEMBL12842581 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2HRH1ALDH1A1TSHRTP53 | |
| SCHEMBL10036916 | 0.76 | CHRM1 (0.44) | SMN1; SMN2CHRM1DRD2HRH1CHRM2 | |
| SCHEMBL12881383 | 0.75 | TP53 (0.44) | SMN1; SMN2CHRM1DRD2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8105652-B2 | Methods of making decomposable thin films of polyelectrolytes and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-01-31 | — | — | US | disclosed |