Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 6/20 | 0.39 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL420355 | 0.94 | HRH1 (0.47) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL10036917 | 0.93 | HRH1 (0.45) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL13988123 | 0.93 | SMN1; SMN2 (0.43) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL10036916 | 0.92 | CHRM1 (0.44) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL13670291 | 0.90 | NAAA (0.45) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL13160777 | 0.90 | HRH3 (0.44) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL15315851 | 0.90 | HRH1 (0.44) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL13160749 | 0.90 | CHRM1 (0.41) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL13160756 | 0.90 | SMN1; SMN2 (0.41) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL10015644 | 0.88 | CHRM1 (0.45) | CHRM1CHRM2CHRM4CHRM5DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170258738-A1 | Multilayer Compositions, Coated Devices And Use Thereof | DEPARTMENT OF DEFENSE | 2017-09-14 | — | — | US | disclosed |
| US-9700627-B2 | Biodegradable poly (beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-07-11 | — | — | US | disclosed |
| US-9700627-B2 | Biodegradable poly (beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-07-11 | — | — | US | disclosed |
| US-20170181981-A1 | BIODEGRADABLE FREE-STANDING CONTROLLED DRUG RELEASE STICKERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-06-29 | — | — | US | disclosed |
| US-20170181981-A1 | BIODEGRADABLE FREE-STANDING CONTROLLED DRUG RELEASE STICKERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-06-29 | — | — | US | disclosed |
| US-9610252-B2 | Multilayer compositions, coated devices and use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-04-04 | — | — | US | disclosed |
| US-9463244-B2 | Compositions and methods for nucleic acid delivery | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-10-11 | — | — | US | disclosed |
| US-9393217-B2 | Self assembled films for protein and drug delivery applications | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-07-19 | — | — | US | disclosed |
| US-20160022821-A1 | BIODEGRADABLE POLY (BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-28 | — | — | US | disclosed |
| US-9198875-B2 | Controlled delivery of bioactive agents from decomposable films | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-12-01 | — | — | US | disclosed |
| US-8287849-B2 | Biodegradable poly(beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-10-16 | — | — | US | disclosed |
| US-RE43612-E1 | Biodegradable poly(β-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-08-28 | — | — | US | disclosed |
| US-20120065358-A1 | BIODEGRADABLE POLY(BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120027837-A1 | MULTILAYER COATING COMPOSITIONS, COATED SUBSTRATES AND METHODS THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-02-02 | — | — | US | disclosed |
| US-7943179-B2 | Drug delivery particle; useful in genetic vaccination; eg poly(beta-amino esters) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-05-17 | — | — | US | disclosed |
| US-20110059172-A1 | THERAPEUTIC COMPOSITIONS | TZIANABOS ARTHUR | 2011-03-10 | — | — | US | disclosed |
| US-20100040674-A1 | CONTROLLED DELIVERY OF BIOACTIVE AGENTS FROM DECOMPOSABLE FILMS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-02-18 | — | — | US | disclosed |
| US-20100036084-A1 | BIODEGRADABLE POLY(BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-02-11 | — | — | US | disclosed |
| US-20090258045-A1 | STRUCTURES INCLUDING ANTIMICROBIAL PEPTIDES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-10-15 | — | — | US | disclosed |
| US-7427394-B2 | Delivering labile agents; buffering effect; transfecting nucleic acids; nontoxic | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027837-A1 | MULTILAYER COATING COMPOSITIONS, COATED SUBSTRATES AND METHODS THEREOF | BDNF, IAPP, NGF | CHRM1 975/4885CHRM2 984/4885CHRM4 1469/4885 |
| US-20160022821-A1 | BIODEGRADABLE POLY (BETA-AMINO ESTERS) AND USES THEREOF | PARN, PARG, NPEPPS | CHRM1 4451/4885CHRM2 4626/4885CHRM4 4795/4885 |
| US-20090258045-A1 | STRUCTURES INCLUDING ANTIMICROBIAL PEPTIDES | NGLY1, VIP, PCBP1 | CHRM1 4430/4885CHRM2 4713/4885CHRM4 4716/4885 |
| US-20100040674-A1 | CONTROLLED DELIVERY OF BIOACTIVE AGENTS FROM DECOMPOSABLE FILMS | LIPA, ADAM9, TGFB1 | CHRM1 3642/4885CHRM2 3431/4885CHRM4 3603/4885 |
| US-20170258738-A1 | Multilayer Compositions, Coated Devices And Use Thereof | EPHA3, EPHA2, BDNF | CHRM1 1197/4885CHRM2 609/4885CHRM4 743/4885 |
| US-20110059172-A1 | THERAPEUTIC COMPOSITIONS | PHOSPHO1, ACP1, TUBB3 | CHRM1 3744/4885CHRM2 3690/4885CHRM4 4434/4885 |
| US-20170181981-A1 | BIODEGRADABLE FREE-STANDING CONTROLLED DRUG RELEASE STICKERS | PLOD3, CUTA, SLC6A2 | CHRM1 2593/4885CHRM2 1370/4885CHRM4 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.