Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13510585 | 0.92 | MAPT (0.36) | SMN1; SMN2CHRM1CHRM4CHRM2HTR1A | |
| SCHEMBL13510862 | 0.86 | SMN1; SMN2 (0.35) | SMN1; SMN2CHRM1CHRM4CHRM2HTR1A | |
| SCHEMBL12181288 | 0.85 | CHRM1 (0.33) | SMN1; SMN2CHRM1CHRM4CHRM2HTR1A | |
| SCHEMBL10046573 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2CHRM1CHRM4CHRM2HTR1A | |
| SCHEMBL420320 | 0.81 | CHRM1 (0.46) | SMN1; SMN2CHRM1CHRM4CHRM2HTR1A | |
| SCHEMBL13510873 | 0.81 | SMN1; SMN2 (0.34) | SMN1; SMN2CHRM1CHRM4CHRM2HTR1A | |
| SCHEMBL13160756 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2CHRM1CHRM4CHRM2HTR1A | |
| SCHEMBL10036917 | 0.80 | HRH1 (0.45) | SMN1; SMN2CHRM1CHRM4CHRM2HTR1A | |
| SCHEMBL14286145 | 0.79 | HRH3 (0.33) | SMN1; SMN2CHRM1CHRM4CHRM2HTR1A | |
| SCHEMBL10036916 | 0.79 | CHRM1 (0.44) | SMN1; SMN2CHRM1CHRM4CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011140136-A2 | DRUG DELIVERY COATING AND DEVICES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-11-10 | — | — | WO | disclosed |