Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12181288 | 0.87 | CHRM1 (0.33) | HRH3CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL12650304 | 0.87 | SMN1; SMN2 (0.36) | HRH3CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL10046573 | 0.86 | SMN1; SMN2 (0.36) | CHRM1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL19036251 | 0.79 | SMN1; SMN2 (0.40) | HRH3CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL12181600 | 0.79 | SMN1; SMN2 (0.35) | HRH3CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL13510585 | 0.78 | MAPT (0.36) | HRH3CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL13510862 | 0.77 | SMN1; SMN2 (0.35) | CHRM1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL420320 | 0.77 | CHRM1 (0.46) | HRH3CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL18717218 | 0.77 | HRH3 (0.36) | HRH3CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL19036161 | 0.77 | HRH1 (0.41) | HRH3CHRM1CHRM2CHRM4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1903068-A1 | Biodegradable poly(beta-amino esters) and uses thereof | Massachusetts Institute of Technology (MIT) (US) | 2008-03-26 | — | — | EP | disclosed |