Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17636107 | 0.97 | SIGMAR1 (0.45) | SIGMAR1CYP2A6CYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL13666236 | 0.91 | SIGMAR1 (0.46) | SIGMAR1CYP2A6CYP1A2ALDH1A1DHFR | |
| SCHEMBL8040513 | 0.91 | SIGMAR1 (0.47) | SIGMAR1CYP2A6CYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL12249724 | 0.90 | SIGMAR1 (0.46) | SIGMAR1CYP2A6CYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL12249727 | 0.89 | SIGMAR1 (0.41) | SIGMAR1CYP2A6CYP1A2ALDH1A1MAOA | |
| SCHEMBL5385549 | 0.88 | SIGMAR1 (0.43) | SIGMAR1CYP2A6CYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL9617133 | 0.88 | SIGMAR1 (0.47) | SIGMAR1CYP2A6CYP1A2ALDH1A1MAOA | |
| SCHEMBL10338332 | 0.88 | SIGMAR1 (0.47) | SIGMAR1CYP2A6CYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL13720871 | 0.87 | SIGMAR1 (0.44) | SIGMAR1CYP2A6CYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL4580938 | 0.87 | SIGMAR1 (0.44) | SIGMAR1CYP2A6CYP1A2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11917913-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2024-02-27 | — | — | US | disclosed |
| US-11917913-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2024-02-27 | — | — | US | disclosed |
| US-10868254-B2 | Phosphorescent OLED and hole transporting materials for phosphorescent OLEDS | NOVALED GMBH (DE) | 2020-12-15 | — | — | US | disclosed |
| US-10868254-B2 | Phosphorescent OLED and hole transporting materials for phosphorescent OLEDS | NOVALED GMBH (DE) | 2020-12-15 | — | — | US | disclosed |
| EP-2909872-B1 | PHOSPHORESCENT OLED AND HOLE TRANSPORTING MATERIALS FOR PHOSPHORESCENT OLEDS | NOVALED GMBH (DE) | 2020-01-08 | — | — | EP | disclosed |
| US-20190280218-A1 | SUBSTITUTED OXEPINES | MERCK PATENT GMBH (DE) | 2019-09-12 | — | — | US | disclosed |
| US-10374170-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2019-08-06 | — | — | US | disclosed |
| US-20190198767-A1 | Phosphorescent OLED and Hole Transporting Materials for Phosphorescent OLEDS | NOVALED GMBH (DE) | 2019-06-27 | — | — | US | disclosed |
| US-20190198767-A1 | Phosphorescent OLED and Hole Transporting Materials for Phosphorescent OLEDS | NOVALED GMBH (DE) | 2019-06-27 | — | — | US | disclosed |
| EP-2673249-B1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2019-04-03 | — | — | EP | disclosed |
| US-20130261708-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| US-20130253617-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| US-20130253617-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| US-20130116755-A1 | METAL COMPLEXES WITH ORGANIC LIGANDS AND USE THEREOF IN OLEDS | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20130116755-A1 | METAL COMPLEXES WITH ORGANIC LIGANDS AND USE THEREOF IN OLEDS | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| WO-2012175536-A1 | DYES, METHOD OF MAKING THEM, AND THEIR USE IN DYE-SENSITIZED SOLAR CELLS | SOLVAY SA (BE) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012107163-A1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |
| WO-2012079678-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012038029-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012007103-A1 | METAL COMPLEXES WITH ORGANIC LIGANDS AND USE THEREOF IN OLEDS | MERCK PATENT GMBH (DE) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11917913-B2 | Substituted oxepines | OXGR1, OXTR, OCIAD2 | SIGMAR1 424/4885CYP2A6 3975/4885CYP1A2 885/4885 |
| US-10868254-B2 | Phosphorescent OLED and hole transporting materials for phosphorescent OLEDS | SLC29A1, SLC43A3, NUDT1 | SIGMAR1 1429/4885CYP2A6 2645/4885CYP1A2 2771/4885 |
| US-20190198767-A1 | Phosphorescent OLED and Hole Transporting Materials for Phosphorescent OLEDS | SLC29A1, SLC43A3, NUDT1 | SIGMAR1 1429/4885CYP2A6 2645/4885CYP1A2 2771/4885 |
| US-10374170-B2 | Substituted oxepines | OXGR1, OXTR, OCIAD2 | SIGMAR1 424/4885CYP2A6 3975/4885CYP1A2 885/4885 |
| US-20190280218-A1 | SUBSTITUTED OXEPINES | OXGR1, OXTR, OCIAD2 | SIGMAR1 424/4885CYP2A6 3975/4885CYP1A2 885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.