SCHEMBL10046777

SCHEMBL10046777

CC(=O)OC1(C)CCCCC1O

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.41
CYP19A1 P11511 1/20 0.32
EP300 Q09472 1/20 0.31
HIF1A Q16665 1/20 0.31
CREBBP Q92793 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29264626 0.79 ALOX15 (0.40) ALOX15CYP19A1EP300HIF1ACREBBP
Hydrochloric Acid SCHEMBL29264624 0.79 ALOX15 (0.40) ALOX15CYP19A1EP300HIF1ACREBBP
Hydrochloric Acid SCHEMBL1705692 0.79 ALOX15 (0.40) ALOX15CYP19A1EP300HIF1ACREBBP
Hydrochloric Acid SCHEMBL29264625 0.79 ALOX15 (0.40) ALOX15CYP19A1EP300HIF1ACREBBP
SCHEMBL21287026 0.79 CYP2C19 (0.33)
SCHEMBL7265074 0.79
SCHEMBL11153344 0.78 ALOX15 (0.39) ALOX15CYP19A1EP300HIF1ACREBBP
SCHEMBL8444775 0.78 ALOX15 (0.39) ALOX15CYP19A1EP300HIF1ACREBBP
SCHEMBL11146106 0.78 ALOX15 (0.39) ALOX15CYP19A1EP300HIF1ACREBBP
SCHEMBL8674651 0.77 ALOX15 (0.38) ALOX15EP300HIF1ACREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8115029-B2 Oxidizing a substrate using a catalyst of a complex of cobalt and N-hydroxysuccinimide, N-hydroxyphthalimide, or N-hydroxymaleimide; alkanes, alkenes, cycloalkanes, cycloalkenes, aromatics, aryl aldehydes, aryl carboxylic acids, benzyl alcohols UNIVERSITY OF KANSAS (US) 2012-02-14 US disclosed
US-8115029-B2 Oxidizing a substrate using a catalyst of a complex of cobalt and N-hydroxysuccinimide, N-hydroxyphthalimide, or N-hydroxymaleimide; alkanes, alkenes, cycloalkanes, cycloalkenes, aromatics, aryl aldehydes, aryl carboxylic acids, benzyl alcohols UNIVERSITY OF KANSAS (US) 2012-02-14 US disclosed
US-20080139841-A1 Cobalt-Catalyzed Oxidations in Volumetrically Expanded Liquids by Compressed Gases UNIVERSITY OF KANSAS (US) 2008-06-12 US disclosed
US-20080139841-A1 Cobalt-Catalyzed Oxidations in Volumetrically Expanded Liquids by Compressed Gases UNIVERSITY OF KANSAS (US) 2008-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080139841-A1 Cobalt-Catalyzed Oxidations in Volumetrically Expanded Liquids by Compressed Gases HAO2, HMOX2, HAAO ALOX15 88/4885CYP19A1 168/4885EP300 1295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.