SCHEMBL10048246

SCHEMBL10048246

C1=Cc2c(n(-c3cccc(-c4cccc(-c5cc(-c6ccccc6)cc(-c6ccccc6)c5)n4)n3)c3ccccc23)CN1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10047771 0.88 TUBB4A (0.30)
SCHEMBL9261877 0.87 TUBB4A (0.31)
SCHEMBL4561656 0.87 TUBB4A (0.31)
SCHEMBL10047761 0.85
SCHEMBL4561489 0.84 KDM4E (0.34) KMT2A
SCHEMBL4562453 0.84 HSD11B1 (0.32)
SCHEMBL4562077 0.83 NISCH (0.33)
SCHEMBL4561426 0.83
SCHEMBL9264548 0.83 HSD11B1 (0.33)
SCHEMBL10048449 0.81 KARS1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2053051-B1 COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2012-05-02 EP disclosed